TRIPHENYLPHOSPHINE DIBROMIDE (cas 1034-39-5): A useful reagent for conversion of aldoximes into nitriles

Add time:07/22/2019    Source:sciencedirect.com

A simple and convenient method for the synthesis of nitriles by dehydration of aldoximes has been developed using triphenylphosphine dibromide in acetonitrile at room temperature. A variety of aromatic and heteroaromatic aldoximes are converted into the corresponding nitriles in high yields.

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