Aristolochic acid I is a substrate of BCRP but not P-glycoprotein or MRP2
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Add time:07/25/2019 Source:sciencedirect.com
Ethnopharmacological relevanceAristolochic acid nephropathy is a severe kidney disease caused by the administration of aristolochic acid, which is widely existed in plants of the Aristolochiaceae family. Aristolochic acid I (AAI) is the main toxic component in aristolochic acid.
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