Comparative effects of leucomyosuppressin (cas 106884-19-9) on the visceral muscle systems of the cockroach Leucophaea maderae
-
Add time:08/10/2019 Source:sciencedirect.com
1. leucomyosuppressin (cas 106884-19-9) (LMS) did not inhibit the spontaneous contractions of visceral muscles of the cockroach Leucophaea maderae uniformly as a group but rather showed a selective suppression of activity in the foregut and hindgut. The threshold of LMS inhibition for these organs was 10−11 M for the foregut and 3 × 10−11 M for the hindgut. The maximum response for each organ was generally recorded at 2.4 × 10−11 M.2. Both the heart and the oviduct were 100–1000 times less sensitive to LMS than either the foregut or the hindgut. Although the responses of the heart to LMS (10−9 to 10−8 M) were somewhat inconsistent, the myocardium showed a reduction in either the amplitude or frequency of contractions in 75% of the preparations tested. The oviduct showed the lowest level of responsiveness of all the muscles tested. Even at a concentration of 10−7 M LMS, the amplitude and frequency of contractions showed no more than a 58% inhibition.3. Desensitization to LMS was observed in three of the four muscle types tested. The phenomenon occurred in 37% of the foreguts, 34% of the hindguts and 54% of the heart preparations tested. The results of this study show that each visceral muscle type has its own unique response profile to LMS and support the idea that peptides may be multifunctional regulators.
We also recommend Trading Suppliers and Manufacturers of leucomyosuppressin (cas 106884-19-9). Pls Click Website Link as below: cas 106884-19-9 suppliers
Prev:Degradation of leucomyosuppressin (cas 106884-19-9) by enzymes in the hemolymph and midgut of Lacanobia oleracea and Spodoptera littoralis (Lepidoptera: Noctuidae) larvae
Next:Effects of leucomyosuppressin (cas 106884-19-9) on the excitation-concentration coupling of insect Leucophaea maderae visceral muscle) - 【Back】【Close 】【Print】【Add to favorite 】
- Related Information
- The muscular contractions of the midgut of the cockroach, Diploptera punctata: effects of the insect neuropeptides proctolin and leucomyosuppressin (cas 106884-19-9)08/14/2019
- leucomyosuppressin (cas 106884-19-9), a novel insect neuropeptide, inhibits evoked transmitter release at the mealworm neuromuscular junction08/13/2019
- Isolation, primary structure and synthesis of leucomyosuppressin (cas 106884-19-9), an insect neuropeptide that inhibits spontaneous contractions of the cockroach hindgut08/12/2019
- Effects of leucomyosuppressin (cas 106884-19-9) on the excitation-concentration coupling of insect Leucophaea maderae visceral muscle08/11/2019
- Degradation of leucomyosuppressin (cas 106884-19-9) by enzymes in the hemolymph and midgut of Lacanobia oleracea and Spodoptera littoralis (Lepidoptera: Noctuidae) larvae08/09/2019
- Identification of leucomyosuppressin (cas 106884-19-9) in the German cockroach, Blattella germanica, as an inhibitor of food intake08/08/2019
- Characterization of the gene for leucomyosuppressin (cas 106884-19-9) and its expression in the brain of the cockroach Diploptera punctata08/07/2019
- The cDNA for leucomyosuppressin (cas 106884-19-9) in Blattella germanica and molecular evolution of insect myosuppressins08/06/2019
- leucomyosuppressin (cas 106884-19-9) modulates cardiac rhythm in the cockroach Blattella germanica08/05/2019