alpha-methyltryptophan (cas 13510-08-2) as a therapeutic agent
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Add time:08/10/2019 Source:sciencedirect.com
1. alpha-methyltryptophan (cas 13510-08-2), on administration to experimental animals gives rise to cerebral alpha-methylserotonin, which substitutes for serotonin in certain behavioral and functional tests.2. Such results are consistent wich the similarity of the properties of the two indoleamlnes with respect to storage, uptake and release, as well as with the 5HT2receptor agonist activity of alpha-methylserotonin.3. It is proposed that alpha-methyltryptophan be regarded as a candidate drug for the provision of alpha-methylserotonin as a substitute for serotonin in disorders where the latter amine is thought Co be deficient.
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