High-affinity binding of 3H-glycine and 14C-β-alanine to synaptosomal-mitochondrial fractions of rat CNS regions; Effects of strychnine
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Add time:08/17/2019 Source:sciencedirect.com
“High-affinity” binding of glycine and β-alanine occurred to synaptosomal-mitochondrial fractions of five regions of rat CNS. Strychnine inhibited the binding of β-alanine to a greater extent than that of glycine to particles of cerebral cortex, midbrain, pons and medulla, but not to those of spinal cord. Both glycine- and β-alanine-receptors may be involved in the convulsant action of strychnine.
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