The enantiomeric separation of metipranolol and desacetylmetipranolol on a cellulose tris-3,5-dimethylphenyl-carbamate (cas 110735-13-2) chiral stationary phase
-
Add time:08/19/2019 Source:sciencedirect.com
A high-performance liquid chromatographic (HPLC) method is described for direct separation of the enantiomers of metipranolol and its principal degradation product and main metabolite, desacetylmetipranolol. Separations are performed on a chiral stationary phase of cellulose tris-3,5-dimethylphenyl carbamate (Chiralcel OD), with hexane-propan-2-ol-diethylamine elution and UV detection at 278 nm. The method affords identification and determination of the optical purity of the bulk drug and its formulated ophthalmic products.
We also recommend Trading Suppliers and Manufacturers of cellulose tris-3,5-dimethylphenyl-carbamate (cas 110735-13-2). Pls Click Website Link as below: cas 110735-13-2 suppliers
Prev:Enantioseparation of 15 organic phosphonate esters on the cellulose tris(3,5-dimethylphenyl carbamate) chiral stationary phase by HPLC
Next:Enantiomeric separation of cizolirtine and metabolites on amylose tris (3,5-dimethylphenyl carbamate) chiral stationary phase) - 【Back】【Close 】【Print】【Add to favorite 】
- Related Information
- The new HPLC methodology for the chiral separation of tamsulosin enantiomers on amylose tris(3,5-dimethylphenylcarbamate) stationary phase☆08/22/2019
- Research paperStereoselective adsorption and trans-membrane transfer of propranolol enantiomers using cellulose derivatives08/21/2019
- Enantiomeric separation of cizolirtine and metabolites on amylose tris (3,5-dimethylphenyl carbamate) chiral stationary phase08/20/2019
- Enantioseparation of 15 organic phosphonate esters on the cellulose tris(3,5-dimethylphenyl carbamate) chiral stationary phase by HPLC08/18/2019
- Hybrid monolithic columns coated with cellulose tris(3,5-dimethylphenyl-carbamate) for enantioseparations in capillary electrochromatography and capillary liquid chromatography08/17/2019
- Organic monolithic capillary columns coated with cellulose tris(3,5-dimethylphenyl carbamate) for enantioseparations by capillary HPLC08/16/2019
-
Health and Chemical more >