Total synthesis of carbocyclic analogues of coformycin (cas 11033-22-0)
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Add time:08/16/2019 Source:sciencedirect.com
Four carbocyclic analogues of the ribonucleoside coformycin, including the recently isolated natural product 2, have been synthesised in racemic form. The syntheses were achieved in a convergent and direct manner via palladium(0) catalysed coupling between diazepinones 15 and 16 and the allylic acetate 5.
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