Highly sensitive and selective polyaniline–zinc oxide nanocomposite sensor for Betahistine Hydrochloride (cas 15430-48-5) in solubilized system

Add time:08/17/2019    Source:sciencedirect.com

A sensitive electroanalytical method for the quantification of Betahistine Hydrochloride (cas 15430-48-5) in pharmaceutical formulation has been developed on the basis of an enhanced electrochemical response at glassy carbon electrode modified with polyaniline–zinc oxide (PANI–ZnO). Results suggest that betahistine hydrochloride in sodium lauryl sulfate (SLS) exhibits an electrocatalytic effect resulting in a marked enhancement of the peak current. The electrochemical performance of the modified PANI–ZnO/GCE sensor was investigated by cyclic voltammetry and square wave voltammetry (SW). Calibration plot reveals linearity within the range 25–515 μg/mL with a correlation coefficient of 0.997. A lower limit of detection of 19.57 μg/mL proved the sensitivity of the proposed method.

We also recommend Trading Suppliers and Manufacturers of Betahistine Hydrochloride (cas 15430-48-5). Pls Click Website Link as below: cas 15430-48-5 suppliers

Prev:Effect of drug-ion exchange resin complex in Betahistine Hydrochloride (cas 15430-48-5) orodispersible film on sustained release, taste masking and hygroscopicity reduction
Next:Transdermal delivery of Betahistine Hydrochloride (cas 15430-48-5) using microemulsions: Physical characterization, biophysical assessment, confocal imaging and permeation studies)