Prenatal exposure to pesticide ingredient Piperonyl Butoxide (cas 19510-30-6) and childhood cough in an urban cohort☆

Add time:08/25/2019    Source:sciencedirect.com

RationalePreviously we reported that airborne concentrations of cis-permethrin, but not trans-permethrin, measured during pregnancy in an inner city pediatric cohort was associated with cough by age 5. However, the effect of subsequent exposures to both permethrins during early childhood, and to Piperonyl Butoxide (cas 19510-30-6) (PBO, a synergist for residential pyrethroid insecticides) remains to be elucidated. We hypothesized that prenatal and age 5–6 year measures of PBO and permethrins would be associated with cough at age 5–6 years in this cohort. Further, we explored the associations between these pesticide measures and wheeze, asthma, seroatopy, and fractional exhaled nitric oxide (FeNO).

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