Original articleExposure-response relationships in asthma caused by Tetrachlorophthalic anhydride (cas 117-08-8)☆
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Add time:08/22/2019 Source:sciencedirect.com
Four patients with asthma caused by occupational exposure to tetrachlorophthalic anhydride (TCPA) had dust-challenge tests that used eight different levels of TCPA exposure. Measurements of TCPA in the test-cubicle air ranged from 1.3 to 961.1 μg/m3. The higher exposures provoked definite late or dual asthmatic responses. Smaller, but statistically significant, responses were observed at low exposures. The late asthmatic-response area had a linear relation to the logarithm of TCPA exposure, but the immediate asthmatic response was less closely related to exposure.
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