Original Research ArticleZileuton (cas 111406-87-2) alleviates acute cisplatin nephrotoxicity: Inhibition of lipoxygenase pathway favorably modulates the renal oxidative/inflammatory/caspase-3 axis
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Add time:09/02/2019 Source:sciencedirect.com
ObjectiveThe current study investigated for the first time the possible beneficial effect of zileuton, a selective 5-lipoxygenase inhibitor (5-LOX), against cisplatin-induced acute renal failure.
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