Short CommunicationRelevance of defensin β-2 and α defensins (HNP1-3) in Alzheimer's disease
-
Add time:09/03/2019 Source:sciencedirect.com
The DEFB4 gene copy numbers were investigated in 206 AD patients and in 250 controls. The levels of the human defensin β−2 (hBD2) and α-defensins (HNP 1-3) in the sera and in the cerebrospinal fluid (CSF) of the patients and the controls were determined.Higher copy numbers of the DEFB4 gene was observed in AD patients as compared with the controls. The levels of hBD-2 and HNP 1-3 were significantly elevated in the sera and in the CSF of the AD patientsThese data suggest that both defensin β−2 and α-defensins have potential role in the development of AD.
We also recommend Trading Suppliers and Manufacturers of ALPHA-DEFENSIN-3 (HUMAN) (cas 136661-76-2). Pls Click Website Link as below: cas 136661-76-2 suppliers
Prev:Pravastatin regulates host foreign-body reaction to polyetheretherketone implants via miR-29ab1-mediated SLIT3 upregulation
Next:Upregulated expression of human alpha-defensins 1, 2 and 3 in hypercholesteremia and its relationship with serum lipid levels) - 【Back】【Close 】【Print】【Add to favorite 】
- Related Information
- Short communicationInduction of human defensins by intestinal Caco-2 cells after interactions with opportunistic Candida species09/25/2019
- Vitamin D reduces the inflammatory response by Porphyromonas gingivalis infection by modulating human β-defensin-3 in human gingival epithelium and periodontal ligament cells09/24/2019
- Evaluation of anticancer activity of α-defensins purified from neutrophils trapped in leukoreduction filters09/10/2019
- Regular ArticlesHuman α-Defensins HNPs-1, -2, and -3 in Renal Cell Carcinoma: Influences on Tumor Cell Proliferation09/09/2019
- Detection of individual human neutrophil α-defensins (human neutrophil peptides 1, 2 and 3) in unfractionated gingival crevicular fluid—A MALDI-MS approach09/08/2019
- Identification and overexpression of human neutrophil α-defensins (human neutrophil peptides 1, 2 and 3) in squamous cell carcinomas of the human tongue09/07/2019
- Systematic mutational analysis of human neutrophil α-defensin HNP409/06/2019
- Original ArticleDefining MC1R Regulation in Human Melanocytes by Its Agonist α-Melanocortin and Antagonists Agouti Signaling Protein and β-Defensin 309/05/2019
- Upregulated expression of human alpha-defensins 1, 2 and 3 in hypercholesteremia and its relationship with serum lipid levels09/04/2019
