Stereoselective synthesis of 3,4,5,6-tetrahydroxycyclohexyl β-amino acid derivatives
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Add time:09/07/2019 Source:sciencedirect.com
Stereoselective syntheses of racemic (1S,2R,3R,4R,5S,6R)- and (1S,2R,3R,4S,5S,6R)-3,4,5,6-tetrahydroxy derivatives of 2-aminocyclohexanecarboxylic acid have been achieved by a stereospecific Diels–Alder reaction between furan and maleic anhydride, a Curtius rearrangement and hydroxylation reactions.
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