DMAP-catalyzed cyanation of aldehydes and ketones with ethyl cyanoformate
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Add time:09/30/2019 Source:sciencedirect.com
The cyanation of carbonyl compounds with ethyl cyanoformate is catalyzed by 4-dimethylaminopyridine (DMAP) to afford the corresponding cyanohydrin carbonates in excellent yields. The system provides a convenient method for cyanation of carbonyl compounds without using metal catalysts or solvents.
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