Angiotensin (cas 1407-47-2) II type 2 receptor and Angiotensin (cas 1407-47-2)-converting enzyme 2 mediate ischemic renal injury in diabetic and non-diabetic rats

Add time:09/28/2019    Source:sciencedirect.com

AimDepressor arm of the renin-Angiotensin (cas 1407-47-2) system (RAS) exerts reno-protective effects in chronic kidney diseases like diabetic nephropathy. However, same is still elusive under AKI and hyperglycaemia comorbidity. Hence, the present study delineates the role of angiotensin-II type 2 receptor (AT2R) and angiotensin-converting enzyme 2 (ACE2) in AKI under normal and hyperglycaemia condition.

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