The 2-Hydroxyethyl methacrylate, with its CAS registry number 868-77-9, has the IUPAC name of 2-hydroxyethyl 2-methylprop-2-enoate. For being a kind of colourless liquid, this is soluble in water and is sensitive to air. When comes to its production, it could be prepared by the reaction of ethylene oxide and methacrylic acid.

The characteristics of 2-Hydroxyethyl methacrylate are as follows:
 (1)ACD/LogP: 0.43; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): 0.427; (4)ACD/LogD (pH 7.4): 0.427; (5)ACD/BCF (pH 5.5): 1.244; (6)ACD/BCF (pH 7.4): 1.244; (7)ACD/KOC (pH 5.5): 40.696; (8)ACD/KOC (pH 7.4): 40.696; (9)#H bond acceptors: 3; (10)#H bond donors: 1; (11)#Freely Rotating Bonds: 5; (12)Polar Surface Area: 46.53; (13)Index of Refraction: 1.443; (14)Molar Refractivity: 32.724 cm³; (15)Molar Volume: 123.459 cm³; (16)Polarizability: 12.973×10^-24 cm³; (17)Surface Tension: 33.723 dyne/cm; (18)Density: 1.054 g/cm³; (19)Flash Point: 97.222 °C; (20)Enthalpy of Vaporization: 49.49 kJ/mol; (21)Boiling Point: 189.031 °C at 760 mmHg; (22)Vapour Pressure: 0.159 mmHg at 25°C; (23)Exact Mass: 130.062994; (24)MonoIsotopic Mass: 130.062994; (25)Topological Polar Surface Area: 46.5; (26)Heavy Atom Count: 9; (27)Complexity: 118.

Production method of 2-Hydroxyethyl methacrylate:
oxirane could react with 2-methyl-acrylic acid to produce Ethylene glycol methacrylate. This reaction could happen in the presence of the reagent of Py, Cu(OAc)₂.


Use of 2-Hydroxyethyl methacrylate:
Ethylene glycol methacrylate could react with isobutyryl chloride to produce 1-isobutyryloxy-2-methacryloyloxy-ethane. This reaction could happen in the presence of the reagent of pyridine.


Safety information of 2-Hydroxyethyl methacrylate:
When you are dealing with 2-Hydroxyethyl methacrylate, you should be very careful. This is irritating to eyes, respiratory system and skin and may cause inflammation to the skin or other mucous membranes. And it may cause sensitisation by skin contact. Therefore, you should wear suitable protective clothing and gloves. If in case of contact with eyes, rinse immediately with plenty of water and seek medical advice, and after contact with skin, wash immediately with plenty of ... (to be specified by the manufacturer).

In addition, you could convert the following datas into the molecular structure:
(1)Canonical SMILES: CC(=C)C(=O)OCCO
(2)InChI: InChI=1S/C6H10O3/c1-5(2)6(8)9-4-3-7/h7H,1,3-4H2,2H3
(3)InChIKey: WOBHKFSMXKNTIM-UHFFFAOYSA-N 

Below are the toxicity information of 2-Hydroxyethyl methacrylate: