Welcome to LookChem.com Sign In|Join Free

CAS

  • or
3-Phenyl-propionamide, also known as N-phenylpropionamide or benzylpropanamide, is a chemical compound that features a benzene ring connected to a propanamide group. This structure endows it with potential applications in various fields, including pharmaceuticals and specialty chemicals.

102-93-2 Suppliers

Post Buying Request

Recommended suppliersmore

  • Product
  • FOB Price
  • Min.Order
  • Supply Ability
  • Supplier
  • Contact Supplier
  • 102-93-2 Structure
  • Basic information

    1. Product Name: Benzenepropanamide
    2. Synonyms: 3-phenyl-propionamide;gamma-phenyl-propionamide;2-Benzylacetamide;3-Phenylpropanamide;Benzenepropanamide
    3. CAS NO:102-93-2
    4. Molecular Formula: C9H11NO
    5. Molecular Weight: 149.18974
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 102-93-2.mol
  • Chemical Properties

    1. Melting Point: 99.0 to 103.0 °C
    2. Boiling Point: 339.851 °C at 760 mmHg
    3. Flash Point: 159.336 °C
    4. Appearance: /
    5. Density: 1.069 g/cm3
    6. Vapor Pressure: 8.94E-05mmHg at 25°C
    7. Refractive Index: 1.543
    8. Storage Temp.: Sealed in dry,Room Temperature
    9. Solubility: N/A
    10. PKA: 16.45±0.40(Predicted)
    11. CAS DataBase Reference: Benzenepropanamide(CAS DataBase Reference)
    12. NIST Chemistry Reference: Benzenepropanamide(102-93-2)
    13. EPA Substance Registry System: Benzenepropanamide(102-93-2)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: 24/25
    4. WGK Germany:
    5. RTECS: MW4905500
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 102-93-2(Hazardous Substances Data)

102-93-2 Usage

Uses

Used in Pharmaceutical Industry:
3-Phenyl-propionamide is used as a starting material or intermediate for the synthesis of more complex organic molecules, which can be further developed into pharmaceuticals. Its unique structure allows for the creation of new drugs with potential therapeutic applications.
Used in Specialty Chemicals Industry:
3-Phenyl-propionamide is used as a building block for the production of specialty chemicals, which can be utilized in various applications such as dyes, pigments, and other industrial processes. Its versatility in chemical reactions makes it a valuable component in the synthesis of these compounds.
Used in Research and Development:
3-Phenyl-propionamide is used as a research compound in academic and industrial laboratories, where it can be studied for its chemical properties and potential applications. This can lead to the discovery of new reactions, synthesis methods, or even new uses in various industries.

Check Digit Verification of cas no

The CAS Registry Mumber 102-93-2 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 1,0 and 2 respectively; the second part has 2 digits, 9 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 102-93:
(5*1)+(4*0)+(3*2)+(2*9)+(1*3)=32
32 % 10 = 2
So 102-93-2 is a valid CAS Registry Number.
InChI:InChI=1/C9H11NO/c10-9(11)7-6-8-4-2-1-3-5-8/h1-5H,6-7H2,(H2,10,11)

102-93-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name 3-phenylpropanamide

1.2 Other means of identification

Product number -
Other names Ph-CH2CH2-CO-NH2

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:102-93-2 SDS

102-93-2Relevant articles and documents

Supported Gold Nanoparticles-Catalyzed Microwave-Assisted Hydration of Nitriles to Amides under Base-Free Conditions

Kumar, Sandeep,Sharma, Saurabh,Das, Pralay

, p. 2889 - 2894 (2016)

Polystyrene-supported gold (Au@PS) nanoparticles were synthesized by the reduction deposition approach and well characterized by UV-visible, XRD, TEM, SAED, EDX, and XPS studies. The Au@PS was applied as catalyst for the hydration of nitriles to amides in water under microwave irradiation. Several functionalized aromatic, heterocyclic and aliphatic nitriles were found to be active for synthesis of the corresponding amides where no activation of water by base, ligand and support is needed. Easy recovery, negligible leaching and recyclability for up to eight runs are added advantages of the catalyst under water-mediated reaction conditions. (Figure presented.).

Convenient removal of N-tert-butyl from amides with scandium triflate

Mahalingam,Wu, Xiongyu,Alterman, Mathias

, p. 3051 - 3053 (2006)

Scandium triflate has been used as a convenient and efficient catalyst for removal of N-tert-butyl from amide groups. A variety of N-tert-butyl aryl and alkyl amides under these conditions gave the corresponding primary amide in high yields. With the use of microwave heating the deprotection reaction could be completed within 1 h.

A selective hydration of nitriles catalysed by a Pd(OAc)2-based system in water

Sanz Sharley, Daniel D.,Williams, Jonathan M.J.

, p. 4090 - 4093 (2017)

In situ formation of a [Pd(OAc)2bipy] (bipy = 2,2′-bipyridyl) complex in water selectively catalyses the hydration of a wide range of organonitriles at 70 °C. Catalyst loadings of 5 mol% afford primary amide products in excellent yields in the absence of hydration-promoting additives such as oximes and hydroxylamines.

Selective hydrogenation of α,β-unsaturated carbonyl compounds on silica-supported copper nanoparticles

Mendes-Burak, Jorge,Ghaffari, Behnaz,Copéret, Christophe

, p. 179 - 181 (2019)

Silica-supported copper nanoparticles prepared via surface organometallic chemistry are highly efficient for the selective hydrogenation of various α,β-unsaturated carbonyl compounds yielding the corresponding saturated esters, ketones, and aldehydes in the absence of additives. High conversions and selectivities (>99%) are obtained for most substrates upon hydrogenation at 100-150 °C and under 25 bar of H2.

Efficient and selective hydration of nitriles to amides in aqueous systems with Ru(II)-phosphaurotropine catalysts

Bolyog-Nagy, Evelin,Udvardy, Antal,Joó, Ferenc,Kathó, ágnes

, p. 3615 - 3617 (2014)

A simple and efficient synthesis of amides by selective hydration of aromatic and aliphatic nitriles is described. The catalysts are prepared in situ from easily available Ru-precursors and ligands using water as the solvent. The most active catalyst, is obtained from [RuCl2(dmso)4] and benzylated 1,3,5-triaza-7-phosphaadamantane. Of the 16 substrates examined, 92-99% conversions of 14 nitriles were achieved in one hour at reflux temperature.

β-cyclodextrin and hydripentacyanocobaltate catalyzed selective hydrogenation of α,β,-unsaturated acids and their derivatives

Lee,Alper

, p. 1941 - 1942 (1990)

Hydrogenation of the double bond of α,β-unsaturated acids, esters, anhydrides, amides, and nitriles occurs in good to excellent yields using in situ generated HCo(CN)5-3, and β-cyclodextrin as the phase transfer catalyst. Hydrolysis of the acid derivative usually accompanies double bond reduction.

Highly Active Platinum Catalysts for Nitrile and Cyanohydrin Hydration: Catalyst Design and Ligand Screening via High-Throughput Techniques

Xing, Xiangyou,Xu, Chen,Chen, Bo,Li, Chengcheng,Virgil, Scott C.,Grubbs, Robert H.

, p. 17782 - 17789 (2018)

Nitrile hydration provides access to amides that are indispensable to researchers in chemical and pharmaceutical industries. Prohibiting the use of this venerable reaction, however, are (1) the dearth of biphasic catalysts that can effectively hydrate nitriles at ambient temperatures with high turnover numbers and (2) the unsolved challenge of hydrating cyanohydrins. Herein, we report the design of new "donor-acceptor"-type platinum catalysts by precisely arranging electron-rich and electron-deficient ligands trans to one other, thereby enhancing both the nucleophilicity of the hydroxyl group and the electrophilicity of the nitrile group. Leveraging a high-throughput, automated workflow and evaluating a library of bidentate ligands, we have discovered that commercially available, inexpensive DPPF [1,1′-ferrocenendiyl-bis(diphenylphosphine)] provides superior reactivity. The corresponding "donor-acceptor"-type catalyst 2a is readily prepared from (DPPF)PtCl2, PMe2OH, and AgOTf. The enhanced activity of 2a permits the hydration of a wide range of nitriles and cyanohydrins to proceed at 40 °C with excellent turnover numbers. Rational reevaluation of the ligand structure has led to the discovery of modified catalyst 2c, harboring the more electron-rich 1,1′-bis[bis(5-methyl-2-furanyl)phosphino] ferrocene ligand, which demonstrates the highest activity toward hydration of nitriles and cyanohydrins at room temperature. Finally, the correlation between the electron-donating ability of the phosphine ligands with catalyst efficiencies of 2a, 2c, 2d, and 2e in the hydration of nitrile 7 are examined, and the results support the "donor-acceptor" hypothesis.

Heck-type coupling vs. conjugate addition in phosphine-rhodium catalyzed reactions of aryl boronic acids with α,β-unsaturated carbonyl compounds: A systematic investigation

Zou, Gang,Guo, Jianping,Wang, Zhiyong,Huang, Wen,Tang, Jie

, p. 3055 - 3064 (2007)

The competition between Heck-type coupling and conjugate addition in phosphine-rhodium catalyzed reactions of aryl boronic acids with α,β-unsaturated carbonyls has been systematically investigated in a toluene-H2O biphasic system. Aside from the intrinsic nature of rhodium and the enolization of carbonyls, the phosphine supporting ligand on rhodium, the ratio of aryl boronic acid to α,β-unsaturated carbonyl and the pH value of the aqueous phase were found to affect the competition significantly. Highly selective rhodium-based catalyst systems have therefore been developed for both Heck-type coupling and conjugate addition by synergistically tuning the supporting ligand, the boronic acid to olefin ratio and other reaction conditions. Conjugate addition with selectivity >99% and Heck-type coupling with selectivity of up to 100%, 98% and 84% for acrylates, acrylamides and methyl vinyl ketone, respectively, could be achieved in the rhodium-catalyzed reactions of aryl boronic acids with α,β- unsaturated carbonyls using the corresponding optimized rhodium-based catalyst systems. The Royal Society of Chemistry.

Titanocene-catalyzed conjugate reduction of αβ-unsaturated carbonyl derivatives

Ashfeld, Brandon L.,Kosal, Andrew D.

, p. 44 - 47 (2010)

"Chemical Equation Presented" A titanocene-catalyzed conjugate reduction of αβ-unsaturated carbonyl derivatives has been developed. A series of carbonyl compounds including aldehydes, ketones, esters, and amides proved viable in the reduction process providing an efficient, chemoselective method for the catalytic reduction of unsaturated carbonyl derivatives.

Solid-supported ruthenium(0): An efficient heterogeneous catalyst for hydration of nitriles to amides under microwave irradiation

Kumar, Sandeep,Das, Pralay

, p. 2987 - 2990 (2013)

Solid-supported ruthenium(0) was synthesized by the reduction deposition method and used as a heterogeneous catalyst for the hydration of nitriles to amides under microwave irradiation. A wide range of aromatic, α,β-unsaturated and aliphatic nitriles were efficiently converted to their corresponding primary amides under milder conditions. The catalyst was found to be very stable under moisture and microwave irradiation, easily separable from the reaction mixture, to cause negligible metal contamination of the product and was recyclable up to ten times without significant loss of catalytic activity.

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 102-93-2