41604-19-7Relevant articles and documents
A mild and practical synthesis of biphenyl compounds
Liang, Shuang,Cao, Xiaohui,Yan, Xilong,Chen, Ligong
, p. 555 - 556 (2012)
A mild and practical synthetic route for biphenyls is established. Isopropyl nitrite was prepared from sodium nitrite, isopropanol and hydrochloric acid. The biphenyl compounds were obtained from the diazotisation of aniline derivatives with the generated isopropyl nitrite and the coupling reaction with benzene derivatives in the presence of CuCl as a catalyst in good yields.
AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME
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Paragraph 0193-0198; 0229-0233, (2021/04/20)
The present invention relates to an organic light emitting compound which is aromatic amine derivatives expressed as chemical formula A and has excellent light emitting properties such as brightness and light emitting efficiency compared with those of an existing light emitting material. Accordingly, an organic electroluminescent device comprising the same has excellent light emitting properties.
Method for synthesizing biphenyl compounds by adopting microchannel reactor
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Paragraph 0051-0056; 0057-0070, (2021/11/10)
The invention relates to a method for synthesizing biphenyl compounds by adopting a microchannel reactor. The method comprises the following steps: mixing a compound shown in a formula (1), a compound shown in a formula (2), a compound shown in a formula (3) and a copper catalyst in the microchannel reactor, carrying out diazotization coupling reaction, and purifying the obtained reaction product to obtain a compound shown in a formula (4). Compared with the prior art, the micro-channel reactor is adopted, so that the diazotization coupling reaction time is effectively shortened, the reaction stability and efficiency are improved, the reaction yield and purity are improved, and the method has the advantages of environmental protection, safety, simple process, low cost, continuous industrial production and the like.
Aromatic amine derivatives having fluorenyl moiety and organic light-emitting diode including the same
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Paragraph 0215; 0222-0227; 0295-0299, (2020/03/24)
The present invention relates to aromatic amine derivatives with a fluorene structure and a light-emitting element including the same, and more specifically, to an organic light-emitting compound expressed as [Formula A] and a light-emitting element containing the same. [Formula A] In [Formula A], X1 or X8 and Ar1, Ar2 are specifically defined in the description of the invention.
Arenediazonium Tosylates (ADTs) as Efficient Reagents for Suzuki-Miyaura Cross-Coupling in Neat Water
Kutonova, Ksenia V.,Jung, Nicole,Trusova, Marina E.,Filimonov, Victor D.,Postnikov, Pavel S.,Br?se, Stefan
, p. 1680 - 1688 (2017/03/21)
A simple, convenient, and environment-friendly procedure for the preparation of substituted biaryls via Suzuki-Miyaura cross-coupling- was developed. The use of arenediazonium tosylates and corresponding boron compounds allows a conversion in neat water in the presence of commercially available Pd(OAc)2 under mild conditions with tolerance to a wide range of functional groups. A procedure particularly useful for the synthesis of di-ortho-substituted biaryls was developed.
Halodeboronation of organotrifluoroborates using tetrabutylammonium tribromide or cesium triiodide
Yao, Min-Liang,Kabalka, George W.,Blevins, David W.,Reddy, Marepally Srinivasa,Yong, Li
experimental part, p. 3738 - 3743 (2012/06/30)
Halodeboronation of organotrifluoroborates using commercially available tetrabutylammonium tribromide (TBATB) or cesium triiodide in aqueous medium is reported. The mild, transition metal-free method has proven to be tolerant of a wide range of functional groups. High regio- and chemoselectivity are observed. Two synthetic routes to (Z)-dibromoalkenes from alkynes, through stereodefined (Z)-2-bromoalkenyltrifluoroborates and (Z)-1,2-bis(boryl) alkenyltrifluoroborates, have been developed using the TBATB mediated bromodeboronation as the key step.
Synthesis of bromobiphenyls
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, (2008/06/13)
Bromobiphenyls (such as 2-fluoro-4-bromobiphenyl) are synthesized by reacting together a phenylboronic acid (such as phenylboronic acid) and a bromoiodobenzene (such as 2-fluoro-4-bromoiodobenzene). The reaction generally takes place with the aid of a catalyst (such as palladium in a zero valance state) and an inert solvent (such as fluorobenzene). Control of temperature is very important to obtain both an acceptable reaction rate and an acceptable level of terphenyl byproduct.
Processes for the preparation of hydratropic acids
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, (2008/06/13)
Novel processes for making arylpropionic acids are described. One process comprises carboxylating particular Grignard compounds which are the products of a catalyzed reaction between corresponding arylmagnesium bromides and ethylene. Furthermore, the reaction making the particular Grignard compounds is itself novel. Also, an improved method is disclosed for making coupled aryl compounds useful as intermediates for making compounds having a pharmaceutical use. For example, particular biaryls may be used to make some of the Grignard compounds herein from which the arylpropionic acids are made. Finally, an improved bromination is disclosed giving high yields of 4-bromo-2-fluoroaniline, which is thereafter coupled with benzene, then used to make the arylmagnesium bromide reacted with ethylene to obtain the particular Grignard compound and subsequent desired arylpropionic acid, i.e. 2-(2-fluoro-4-biphenylyl)propionic acid.
Process for preparing biaryl compounds via coupling of an arylamine with an arene
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, (2008/06/13)
Improvement in the process for preparing biaryl compounds via coupling of an arylamine with an arene in the presence of a nitrite, an acid and copper metal or a derivative thereof; the improvement is consisting in adding to the reaction mixture a trialkylorthoformate. The process may be used for preparing drugs such as Flurbiprofen and Xenbucin or intermediate compounds particularly useful for preparing Flurbiprofen, Flufenisal, Chlordimorin, Xenbucin, Xenysalate, Xenyhexenic acid and the like.
