531-75-9 Usage
Uses
Used in Pharmaceutical Industry:
Esculin is used as a treatment agent for venous peripheral diseases and hemorrhoids, due to its vasoprotective and venotonic properties.
Used in Cosmetics Industry:
Esculin is used as an active ingredient in the treatment of aging skin, taking advantage of its beneficial effects on the skin's health and appearance.
Used in Tanning Industry:
Esculin is used as a tanning agent, leveraging its ultraviolet absorbing activity to provide protection and enhance the tanning process.
Used in Research and Diagnostics:
Esculin is used as a substrate for the detection of β-glucosidase activity in polyacrylamide gels, aiding in the identification of specific enzymes and their functions.
Used in Microbiology:
Esculin is used for the identification of bacteria, serving as a valuable tool in the study and classification of various bacterial species.
Used in Cellulite Treatment:
Esculin, in the form of esculoside, is utilized in formulations for the treatment of cellulite, as it is beneficial for improving impaired microcirculation.
Used in Sporulation-inducing Esculin Agar:
Esculin hydrate has been used as a component of sporulation-inducing esculin agar, which is essential for the growth and development of certain microorganisms.
References
[1] Anna D. Orla-Jensen, About the application of aesculin for the identification of bacteria, APMIS, 1934, vol. 11, 312-322
[2] S. Srijayanta, A. Raman and B. L. Goodwin, A comparative study of the constituents of Aesculus hippocastanum and Aesculus indica, Journal of Medical Food, 1999, vol. 2, 45-50
[3] Ki-Sun Kwon, Jaehoon Lee, Hyung Gyoo Kang and Yung Chil Hah, Detection of ?-Glucosidase Activity in Polyacrylamide Gels with Esculin as Substrate, Appl. Environ. Microbil., 1994, vol. 80, 4584-4586
[4] Dennis J Mckenna, Kenneth Jones, Kerry Hughes and Virginia M Tyler, Botanical Medicines: The Desk Reference for Major Herbal Supplements, Second Edition, 2011
Flammability and Explosibility
Notclassified
Biochem/physiol Actions
Esculin is a coumarin glycoside that demonstrates antioxidant activitites and protection against chemically-induced carcinogenesis. Esculin is utilized in microbiology for the isolation and identification of Enterococcus (group D streptococci).
Check Digit Verification of cas no
The CAS Registry Mumber 531-75-9 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 5,3 and 1 respectively; the second part has 2 digits, 7 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 531-75:
(5*5)+(4*3)+(3*1)+(2*7)+(1*5)=59
59 % 10 = 9
So 531-75-9 is a valid CAS Registry Number.
InChI:InChI=1/C15H16O9/c16-5-10-12(19)13(20)14(21)15(24-10)23-9-3-6-1-2-11(18)22-8(6)4-7(9)17/h1-4,10,12-17,19-21H,5H2/t10-,12+,13-,14+,15+/m0/s1
531-75-9Relevant articles and documents
A Switchable Open/closed Polyaromatic Macrocycle that Shows Reversible Binding of Long Hydrophilic Molecules
Kurihara, Kohei,Yazaki, Kohei,Akita, Munetaka,Yoshizawa, Michito
supporting information, p. 11360 - 11364 (2017/09/11)
In spite of wide-ranging previous studies on synthetic macrocycles, the installation of open–close functions into the frameworks remains a challenge. We present a new polyaromatic macrocycle capable of switching between open and closed forms in response to external stimuli, namely, base and acid. The macrocycle, which is prepared in three steps, has a well-defined hydrophobic cavity with a length of around 1 nm, surrounded by four pH-responsive acridinium panels. The open and closed structures were confirmed by single-crystal X-ray analysis. The cylindrical cavity can bind long hydrophilic molecules up to 2.7 nm in length in neutral water and then release the bound guests through a reversible open-to-closed structural change upon simple addition of base.
Amphiphile cyclodextrins, preparation and use thereof for solubilizing organized systems and incorporating hydrophobic molecules
-
, (2008/06/13)
The invention provides cyclodextrin derivatives that may be used to transport hydrophobic molecules for pharmaceutical or cosmetic applications, by forming organised systems in an aqueous medium, alone or with phospholipids. The cyclodextrin derivatives of the present invention have the formula: in which, R1 represents a steroid, R2 represents an alkyl or aryl group, substituted if applicable, R3 represents H or R2, all the R4 represent OR2, or one of the R4 represents —NHCO(CH2)mCONHR1, m is an integer ranging from 1 to 8, and n is equal to 5, 6 or 7.
Fermented milk product
-
, (2008/06/13)
Lactic acid bacteria of the genus Lactobacillus having the following specific properties: (1) an increased amount of acidity of lactic acid when storing a product cultured by the bacteria at 10° C. for two weeks being 0.5% or less; (2) an activity of cell membrane bound adenosine triphosphatase-being 5 μmol.Pi/min/mg protein or less; and (3) the bacteria having neomycin resistance. Furthermore, a fermented milk product containing the lactic acid bacteria is disclosed.
