650-51-1 Usage
Uses
Used in Microscopy:
Sodium trichloroacetate is used as a decalcifier and fixative in microscopy, helping to preserve and prepare samples for examination.
Used in Protein Precipitation:
It is also used as a precipitant of protein, aiding in the separation and purification of proteins in various applications.
Used in Herbicide Formulations:
Sodium trichloroacetate is used in herbicide formulations to control the growth of unwanted plants.
Used in Textile Industry:
In the textile industry, sodium trichloroacetate is used as an acid binding reagent in the dyeing process, helping to improve the colorfastness and quality of dyed fabrics.
Used in Protein Denaturation:
Sodium trichloroacetate has been reported to be an effective denaturation reagent for proteins. It has been applied to poly(l-lysine) and poly(l-glutamic acid) to study its effects on a coil-to-helix transition and on the chemical reactivities of the ε-amino group of poly(l-lysine). The addition of sodium trichloroacetate to poly-(l-lysine) induces a helical conformation even at neutral pH where the ε-amino group of the polymer is protonated.
Used in Organic Synthesis:
Sodium trichloroacetate, in combination with trichloroacetic acid (TCA), undergoes rapid decarboxylation in dimethylformamide (DMF) in the presence of aldehydes to form nucleophilic trichloromethyl anion, which then adds to the aldehydes to form trichloromethyl carbinols. It can also undergo thermal decarboxylation in aprotonic solvents in the presence of olefins to generate dichlorocarbene as an intermediate, which can be used in various organic synthesis reactions.
Hazard
Toxic by ingestion, irritant to skin and eyes.
Flammability and Explosibility
Nonflammable
Safety Profile
Moderately toxic by ingestion andintravenous routes. Human mutation data reported. Largedoses cause central nervous system depression. Used as anherbicide. Bags of the salt can ignite spontaneously instorage. When heated to decomposition it emits very
Check Digit Verification of cas no
The CAS Registry Mumber 650-51-1 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 6,5 and 0 respectively; the second part has 2 digits, 5 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 650-51:
(5*6)+(4*5)+(3*0)+(2*5)+(1*1)=61
61 % 10 = 1
So 650-51-1 is a valid CAS Registry Number.
InChI:InChI=1/C2HCl3O2/c3-2(4,5)1(6)7/h(H,6,7)
650-51-1Relevant articles and documents
Effect of solvating additives on anion-exchange extraction of trichloroacetate anions from aqueous solutions with trinonyloctadecylammonium picrate in toluene
Rakhma'ko,Gulevich,Kiiko,Kovalevich
, p. 69 - 73 (2008/02/04)
The solvation effect of trifluoroacetophenone derivatives on anion-exchange extraction of trichloroacetate anions from aqueous phase with trinonyloctadecylammonium picrate in toluene was studied. Pleiades Publishing, Inc., 2006.
Wood preservative compositions
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, (2008/06/13)
Biocidal compositions formed by metathesis or acid-base reactions by combing either monomeric or polymeric bioactive cations with either bioactive monomeric or polymeric anions or by the reaction of a free base with an organic compound capable of donating a proton to the free base to form an essentially water insoluble complexes. Said complexes can be solubilized to yield water-soluble emulsions or microemulsions. These novel and unique compositions are effective wood preservative, which are totally organic substances not having any toxic heavy metal ions present.
Trihalocyclopropyl carbonates
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, (2008/06/13)
When the reaction of aldehydes with alkali metal trihaloacetates is carried out in the presence of a highly polar aprotic solvent (DMF, DMSO), novel organic alkali metal carbonates, which are precursors of pyrethroid insecticides, are formed in high yields and at a high rate. Novel sulfonates and dihalophosphites, derived from these carbonates have also been claimed.
