- Observation of an isolated intermediate of the nucleophilic aromatic substition reaction by infrared spectroscopy
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(Figure Presented) Caught in the act: The σ complex formed as an intermediate in a nucleophilic aromatic substitution has been observed experimentally. Efficient direct ionization of C6F6 by coherent vacuum ultraviolet light was employed to effect the formation of C 6F5NH2 + from C6F 6 +/NH3. Comparison of the IR spectrum of (C6F6-NH3)+ with that predicted from DFT calculations showed that the cluster cation forms a stable σ complex (see picture).
- Hasegawa, Hayato,Mizuse, Kenta,Hachiya, Masaki,Matsuda, Yoshiyuki,Mikami, Naohiko,Fujii, Asuka
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Read Online
- Syntheses of Transition Metal Complexes of Pentafluorophenylhydrazine
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By reaction of pentafluorophenylhydrazine with metal chlorides the complexes M(NH2NHC6F5)4Cl2 (M = Co, Ni), M(NH2NHC6F5)2Cl2 (M = Mn, Fe, Pd, Zn,
- Rieber, Wolfram,Beck, Wolfgang
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Read Online
- Biorenewable carbon-supported Ru catalyst for: N -alkylation of amines with alcohols and selective hydrogenation of nitroarenes
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Herein, we developed a renewable carbon-supported Ru catalyst (Ru/PNC-700), which was facilely prepared via simple impregnation followed by the pyrolysis process. The prepared Ru/PNC-700 catalyst demonstrated remarkable catalytic activity in terms of conversion and selectivity towards N-alkylation of anilines with benzyl alcohol and chemoselective hydrogenation of aromatic nitro compounds. In addition, local anesthetic pharmaceutical agents (e.g., butamben and benzocaine), including key drug intermediates, were synthesized in excellent yields under mild conditions and in the presence of water as a green solvent. Moreover, the prepared Ru/PNC-700 catalyst could be easily recovered and reused up to five times without any apparent loss in activity and selectivity.
- Goyal, Vishakha,Narani, Anand,Natte, Kishore,Poddar, Mukesh Kumar,Ray, Anjan,Sarki, Naina,Tripathi, Deependra
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p. 14687 - 14694
(2021/08/23)
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- Borane Adducts of Hydrazoic Acid and Organic Azides: Intermediates for the Formation of Aminoboranes
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The reaction of HN3 with the strong Lewis acid B(C6F5)3 led to the formation of a very labile HN3?B(C6F5)3 adduct, which decomposed to an aminoborane, H(C6F5)NB(C6F5)2, above ?20 °C with release of molecular nitrogen and simultaneous migration of a C6F5 group from boron to the nitrogen atom. The intermediary formation of azide–borane adducts with B(C6F5)3 was also demonstrated for a series of organic azides, RN3 (R=Me3Si, Ph, 3,5-(CF3)2C6H3), which also underwent Staudinger-like decomposition along with C6F5 group migration. In accord with experiment, computations revealed rather small barriers towards nitrogen release for these highly labile azide adducts for all organic substituents except R=Me3Si (m.p. 120 °C, Tdec=189 °C). Hydrolysis of the aminoboranes provided C6F5-substituted amines, HN(R)(C6F5), in good yields.
- Bl?sing, Kevin,Bresien, Jonas,Labbow, René,Michalik, Dirk,Schulz, Axel,Thomas, Max,Villinger, Alexander
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supporting information
p. 6540 - 6544
(2019/04/10)
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- Coordination or Oxidative Addition? Activation of N-H with [Tp′Rh(PMe3)]
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A thermal reaction of amines, anilines, and amides with Tp′Rh(PMe3)(CH3)H (1, Tp′ = tris(3,5-dimethyl-pyrazolyl)borate) is described in this report. No N-H bond cleavage was observed for reactions between ammonia or unsubstituted aliphatic amines with the reactive fragment [Tp′Rh(PMe3)]. Instead, amine coordination products (κ2-Tp′)Rh(PMe3)(NHR1R2) (R1 = H, R2 = H, nPr, iPr, octyl; R1 = R2 = Et; R1, R2: pyrrolidine) were observed, and the crystal structure of (κ2-Tp′)Rh(PMe3)(NH2iPr) is reported. No coordination products were observed when 1 was reacted with 1,1,1,3,3,3-hexafluoropropan-2-amine, anilines, and amides. Instead, the oxidative addition products (κ3-Tp′)Rh(PMe3)(NHR)H (R = CH(CF3)2, C6H5, 3,5-dimethylbenzyl, C6F5, C(O)CH3, C(O)CF3) were observed. Both RhI-N coordination products (κ2-Tp′)Rh(PMe3)(NH2CH2CF3) and RhIII N-H addition products (κ3-Tp′)Rh(PMe3)(NHCH2CF3)H were generated when 1 was reacted with 2,2,2-trifluoroethylamine. Coordination products dissociate ammonia and amines in benzene much faster than oxidative addition products eliminate anilines and amides. The relative metal-nitrogen bond energies were studied using established kinetic techniques. Analysis of the relationship between the relative M-N bond strengths and N-H bond strengths showed a linear correlation with a slope = RM-N/N-H of 0.91 (10), indicating that the Rh-N bond strength varies in direct proportion to the N-H bond strength.
- Yuwen, Jing,Brennessel, William W.,Jones, William D.
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supporting information
p. 557 - 566
(2019/01/11)
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- Preparation method of polyfluoroaniline
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The invention relates to a preparation method of polyfluoroaniline, according to the method, the polyfluoroaniline is prepared by a two-step common reaction from polyfluorobenzene as a raw material, the method has the characteristics of low reaction temperature, small pressure, low cost, and the like, is suitable for industrial production application, and is convenient for large-scale production;the polyfluoroaniline product obtained by the method has less impurities and high product purity.
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Paragraph 0062; 0063; 0064; 0065
(2018/08/03)
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- Preparation method for pentafluorophenol
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The invention relates to the field of organic synthesis and especially relates to a preparation method for pentafluorophenol. The preparation method comprises the steps of: 1) a Hoffmann rearrangement reaction: performing the rearrangement reaction to the compound (II) in the presence of alkali and a halogenation reagent to prepare the compound (III); 2) a diazo-hydrolysis reaction: performing a diazotization reaction to the compound (III) with a nitroso compound and performing a hydrolysis reaction in the presence of a catalyst to prepare the compound (I). The raw materials in the method are easy to obtain. The preparation method is short in synthesis route and is mild in reaction conditions, is simple in purification of the product, has high product purity and stable product quality, is low in cost of the whole synthesis route and is suitable for industrial large-scale promotion and application.
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Paragraph 0086-0091
(2017/10/12)
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- Enhanced chemoselective hydrogenation through tuning the interaction between pt nanoparticles and carbon supports: Insights from identical location transmission electron microscopy and x?ray photoelectron spectroscopy
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Ultrasmall-sized platinum nanoparticles (Pt NPs) (～1 nm) supported on carbon nanotubes (CNTs) with nitrogen doping and oxygen functional groups were synthesized and applied in the catalytic hydrogenation of nitroarenes. The advanced identical location transmission electron microscopy (IL-TEM) method was applied to probe the structure evolution of the Pt/CNT catalysts in the reaction. The results indicate that Pt NPs supported on CNTs with a high amount of nitrogen doping (Pt/H-NCNTs) afford 2-fold activity to that of Pt NPs supported on CNTs with oxygen functional groups (Pt/oCNTs) and 4-fold to that of the commercial Pt NPs supported on active carbon (Pt/C) catalyst toward nitrobenzene. The catalytic performance of Pt/H-NCNTs remained constant during four cycles, whereas the activity of the Pt/oCNTs was halved at the second cycle. Compared with Pt/oCNTs, Pt/H-NCNTs exhibited a higher selectivity (>99%) in chemoselective hydrogenation of halonitrobenzenes to haloanilines due to the electron-rich chemical state of Pt NPs. The strong metal?support interaction along with the electron-donor capacity of nitrogen sites on H-NCNTs are capable of stabilizing the Pt NPs and achieving related catalytic recyclability as well as approximately 100% selectivity. The catalyst also delivers exclusively selective hydrogenation toward nitro groups for a wide scope of substituent nitroarenes into their corresponding anilines.
- Shi, Wen,Zhang, Bingsen,Lin, Yangming,Wang, Qi,Zhang, Qiang,Su, Dang Sheng
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p. 7844 - 7854
(2018/05/23)
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- The colloidal synthesis of unsupported nickel-tin bimetallic nanoparticles with tunable composition that have high activity for the reduction of nitroarenes
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Abstract Ni-Sn bimetallic nanoparticles with controllable size and composition were prepared by facile method in ambient air using inexpensive metal salts. Adjusting stoichiometric ratio of Ni and Sn precursors afforded nanoparticles with different compositions, such as Ni100, Ni74-Sn26, Ni59-Sn41, and Ni50-Sn50. The characterization of nanoparticles was performed by powder X-ray diffraction (XRD), transmission electron microscopy (TEM), high resolution transmission electron microscopy (HR-TEM), and energy dispersive X-ray analysis (EDX). Ni75-Sn25 and Ni60-Sn40 nanoparticles showed enhanced catalytic activity towards 2-nitroaniline reduction as compared with Ni nanoparticles. Furthermore, Ni75-Sn25 nanocatalyst exhibited excellent activity for the reduction of a number of nitro aromatic compounds under mild conditions along with high level of reusability.
- Shah, Mazloom,Guo, Qing-Xiang,Fu, Yao
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supporting information
p. 85 - 90
(2015/03/18)
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- Efficient and highly selective boron-doped carbon materials-catalyzed reduction of nitroarenes
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Exploring the potential catalytic applications of boron-doped carbon materials is a fascinating challenge. Here we describe that boron-doped onion-like carbon and carbon nanotubes as metal-free catalysts exhibit excellent catalytic activity and stability in nitroarene reduction under a stoichiometric amount of reductant.
- Lin, Yangming,Wu, Shuchang,Shi, Wen,Zhang, Bingsen,Wang, Jia,Kim, Yoong Ahm,Endo, Morinobu,Su, Dang Sheng
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p. 13086 - 13089
(2015/08/18)
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- Formation of polyfluorinated azobenzenes and azophenols in the reactions of chloropentafluoro-cyclohexa-2,5- and -2,4-dienones with phenyl- and pentafluorophenylhydrazines
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4-Chloropentafluorocyclohexa-2,5-dienone reacted with phenyl- and pentafluorophenylhydrazines in the presence of AlCl3 via addition to the carbonyl group with formation of the corresponding azobenzenes. The reaction of 6-chloropentafluorocycloh
- Kovtonyuk
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- Terminal imido rhodium complexes
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Compounds of the late transition metals with M≡X multiple bonds (X=CR2, NR, O) represent a synthetic challenge, partly overcome by preparative chemists, but with noticeable gaps in the second- and third-row elements. For example, there are no isolated examples of terminal imido rhodium complexes known to date. Described herein is the isolation, characterization, and some preliminary reactivity studies of the first rhodium complexes [Rh(PhBP3)(NR)] (PhBP3=PhB{CH2PPh 2}3) with a multiple and terminal Rh≡N bond. These imido compounds result from reactions of organic azides with the corresponding rhodium(I) complex having a labile ligand, and display a pseudo-tetrahedral core geometry with an almost linear Rh-N-C arrangement [177.5(2)°]] and a short Rh-N bond [1.780(2) A]. We also show that the Rh≡N bond undergoes protonation at the nitrogen atom or addition of H2, and also engages in nitrene-group transfer and cycloaddition reactions. A missing link: Terminal imido rhodium complexes with a Rh≡N multiple bond have been prepared, thus providing compounds which have been elusive to synthesis. Preliminary studies indicate rhodium imides are somewhat ambiphilic and can therefore undergo protonation at the nitrogen atom, as well as hydrogenation at the Rh≡N bond. These systems also engage in nitrene-group transfer and cycloaddition reactions.
- Geer, Ana M.,Tejel, Cristina,Lopez, Jose A.,Ciriano, Miguel A.
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supporting information
p. 5614 - 5618
(2014/06/10)
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- Ethylacetoacetate tagged basic imidazolium salt: Multi-task in CuI nanoparticle catalyzed amination of aryl halides
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Copper catalyzed reactions suffer from harsh conditions of high temperature, high pressure, over-stoichiometric amount of copper reagents and use of expensive ligands. In an attempt to develop a mild, efficient and reusable system for copper catalyzed reactions, ethylacetoacetate was doped into ionic liquid (IL) by tagging it with imidazolium cation stabilized by a counter hydroxide or acetate anion (4a and 4b). The novel ligand-anchored ILs demonstrated high efficiency in generation and stabilization of uniformly dispersed Cu(I)I nanoparticles with particle size in range 9-12 nm. Further, the catalytic system provided an efficient route to amination of aryl iodides, bromides and the less reactive chlorides under mild conditions with very low catalyst loading of only 2 mol % to yield primary aryl amines selectively. Furthermore, the reaction allowed easy isolation of products with recovery of ionic liquid containing an intact built-in ligand and base combination for further reuse.
- Srivastava, Ananya,Jain, Nidhi
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p. 5092 - 5097
(2013/06/27)
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- Copper-catalyzed hydrodefluorination of fluoroarenes by copper hydride intermediates
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Breaking bad: Efficient copper-catalyzed C-F bond activation has been achieved by replacing fluorine with hydrogen. A copper hydride is proposed as the active intermediate, which proceeds through a nucleophilic attack on the fluorocarbon, as determined by experimental and theoretical results (see structure; C gray, H white, Cu light red, F light blue; distances in ?).
- Lv, Hongbin,Cai, Yuan-Bo,Zhang, Jun-Long
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supporting information
p. 3203 - 3207
(2013/04/23)
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- Amino- and hydrodefluorination of polyfluoroaromatic amines with aqueous ammonia in a steel autoclave. Synthesis of highly pure tetrafluorophenylenediamines
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The action of aqueous ammonia on liexafhiorobenzene in a steel autoclave at 180-220 °C yields a mixture of isomeric tet rafluorophenylenediamines and 2,4,5-trifhioroplienylene-1,3-diamine. The content of the hydrodefluorination product significantly depends on the reaction temperature and time. Tetrafluorophenylene-1,3-diamine undergoes hydrodefluorination with aqueous ammonia in a steel autoclave at 200 °C to give 2,4,5-trifluorophenylene-1,3- diamine; when the additives of NH4F and/or FeCl3 are present, 2,5-difluorophenylene-1,3-diamine is additionally formed. The hydrodefluorination products are not formed during bis-aminodefluorination of hexafluorobenzene with aqueous ammonia in a glass reactor or with anhydrous ammonia (in a mixture with aprotic solvent) in a steel autoclave.
- Kusov,Rodionov,Vaganova,Shundrina,Malykhin
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experimental part
p. 823 - 827
(2010/08/08)
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- Selective mono-and diamination of polyfluorinated benzenes and pyridines with liquid ammonia
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Amination of pentafluoropyridine, 2,3,5,6-tetrafluoropyridine, 4-chlorotetrafluoropyridine, 3,5-dichlorotrifluoropyridine, octafluorotoluene, α,α,α,2,3,5,6-heptafluorotoluene, decafluoro-m-xylene, decafluorobiphenyl, hexafluorobenzene, and pentafluorobenzene with liquid ammonia was investigated. Bis-aminodefluorination temperatures for the majority of substrates were shown to exceed significantly the corresponding temperatures of monoaminodefluorination. The optimal conditions for selective preparation of mono-and diaminopolyfluoro(het)arenes were elucidated. An efficient method for isolation of particular polyfluorophenylenediamines from product mixtures formed in nonselective reactions of pentafluorobenzene and hexafluorobenzene with aqueous ammonia based on complexation with a crown ether is proposed.
- Vaganova,Kusov,Rodionov,Shundrina,Malykhin
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p. 2239 - 2246
(2008/09/20)
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- Reactions of N-(perfluorophenyl)carbonimidoyl dichloride with aromatic acids and their derivatives in the presence of AlCl3. Formation of 2-(perfluorophenyl)isoindoline-1,3-dione and its derivatives
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Reactions of N-(perfluorophenyl)carbonimidoyl dichloride with benzoic acid, benzoyl chloride, ethyl benzoate, and also with phthalic acid, phthaloyl dichloride, and phthalic anhydride in the presence of AlCl3 at 170°C afford2-(perfluorophenyl)isoindoline-1,3-dione. With benzoic acid and benzoyl chloride form also 2-(perfluorophenyl)-3-[(perfluorophenyl)imino] isoindolin-1-one. In reactions with compounds of the benzene series arise also derivatives of arylimidoyl chlorides and amide type compounds containing a CONHC6F5 moiety. 2005 Pleiades Publishing, Inc.
- Petrova,Platonov
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p. 218 - 226
(2007/10/03)
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- Non-metallocene compounds, method for the production thereof and use of the same for the polymerisation of olefins
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The invention relates to a method for producing special transition metal compounds, to novel transition metal compounds and to the use of the same for the polymerisation of olefins.
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- Flash Photolytic Decarbonylation and Ring-Opening of 2-(N-(Pentafluorophenyl)amino)-3-phenylcyclopropenone. Isomerization of the Resulting Ynamine to a Ketenimine, Hydration of the Ketenimine, and Hydrolysis of the Enamine Produced by Ring-Opening
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Flash photolysis of 2-(N-(pentafluorophenyl)amino)-3-phenylcyclopropenone, 4, in aqueous solution was found to produce N-(pentafluorophenyl)phenylethynamine, 3, by the expected photodecarbonylation reaction and also 2-phenyl-3-(N-(pentafluorophenyl)amino)acrylic acid, 5, by an apparently unprecedented photochemical ring-opening process. The ynamine underwent rapid isomerization to N-(pentafluorophenyl)phenylketenimine, 9, by an acid-catalyzed route that involves rate- determining proton transfer to the β-carbon atom of the ynamine and also by a base-catalyzed route involving equilibrium ionization of the N-H bond of the ynamine to give an ynamide ion followed by rate-determining β-carbon protonation of this ion. Saturation of the base catalysis allowed determination of the acidity constant of the ynamine; the result, pQa = 10.23, makes this amine a remarkably strong nitrogen acid. Hydration of the ketenimine 9 gave N-(pentafluorophenyl)phenylacetamide, 6, as the ultimate product produced by this reaction route, and hydrolysis of the aminoacrylic acid 5 gave pentafluoroaniline, 7, and 2-phenylformylacetic acid, 10, which underwent decarboxylation to phenylacetaldehyde, 8, as the ultimate products of this route.
- Chiang,Grant,Guo,Kresge,Paine
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p. 5363 - 5370
(2007/10/03)
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- Chemistry and kinetics of singlet (pentafluorophenyl)nitrene
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The chemistry and kinetics of singlet (pentafluorophenyl)nitrene were studied by chemical trapping and laser flash photolysis techniques. Photolysis of pentafluorophenyt azide in cyclohexane, benzene, diethylamine, pyridine, tetramethylethylene, tetrahydrofuran, dimethyl sutfoxide, and dimethyl sulfide forms adducts in fair to good yields. At ambient temperature singlet (pentafluorophenyl)nitrene is intercepted, and intersystem crossing to the lower energy triplet state is unimportant. Triplet nitrene chemistry can be achieved by benzoylbiphenyl photosensitization, the presence of methanol or ethyl iodide, or by lowering the reaction temperature below 0 °C. The singlet nitrenc adduct formed in pyridine is an ylide whose structure has been determined by X-ray crystallography. The ylide has an intense absorption maximum at 390 nm which varies only slightly with solvent. The pyridine ylicle is a useful probe for monitoring the absolute kinetics of singlet (pentafluorophenyl)nitrene by laser flash photolysis techniques.
- Poe, Russell,Schnapp, Karlyn,Young, Mary J.T.,Grayzar, Jennifer,Platz, Matthew S.
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p. 5054 - 5067
(2007/10/02)
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- Polyfluorinated Aryl Azides as Photoaffinity Labelling Reagents; The Room Temperature CH Insertion Reactions of Singlet Pentafluorophenyl Nitrene With Alkanes
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Photolysis of pentafluorophenyl azide in alkanes releases singlet pentafluorophenylnitrene which inserts into the CH bond of cyclopentane to produce an adduct in 28percent yield.
- Young, Mary Jennifer T.,Platz, Matthew S.
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p. 2199 - 2202
(2007/10/02)
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- EQUILIBRIUM NH ACIDITY OF 4-SUBSTITUTED 1-AMINOANTHRAQUINONES IN DIMETHYL SULFOXIDE
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The equilibrium acidity of 1-amino-4-R-anthraquinones (R = CH3O, H, Cl, Br, NO2) was determined by transmetallation in DMSO (the Na+ cation, 25 deg C).A linear correlation was established between the pK values of the 4-substituted 1-aminoanthraquinones and the ?p- constants of the substituents R.The conduction of the electronic effect of the substituents R is stronger in the aminoanthraquinones than in the anilines and is closer to the naphthylamines.A linear relation is observed between the conduction of the electronic effect of the substituent and the square of the coefficient in the HOMO for the carbon atom at the point of addiion of the substituent in the series of anions of NH acids of various structure types.The increase in the NH acidity with change in the structure type of the NH acid is not necessarily accompanied by a decrease in the conduction of the electronic effect of the substituents.
- Os'kina, I. A.,Vlasov, V. M.,Terekhova, M. I.,Petrov, E. S.
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p. 2041 - 2044
(2007/10/02)
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- N-(POLYFLUOROARYL)-HIDROXYLAMINES. SYNTHESIS AND PROPERTIES
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Fluorine-containing N-arylhydroxylamines have been obtained by the reaction of hydroxylamine or its N- and O-derivatives on polyfluorinated benzenes and pentafluoropyridine.The influence of fluorine atoms on the reactivity of hydroxylamino group has been investigated.The reaction of N-polyflouroarylhydroxylamines with aldehydes has been shown not to occur, whereas their reaction with nitrosobenzenes leads to azoxybenzenes and with Lewis acids leads to corresponding nitrosobenzenes, azoxybenzenes and anilines.The action of acids on 2,3,5,6-tetrafluorophenylhydroxylamine leads to the acid-catalyzed rearrangement of the latter into 4-amino-2,3,5,6-tetrafluorophenol.C,N-Diarylnitrones have been obtained by the oxidation with MnO2 of fluorine-containing arylhydroxylamines possessing the CH-fragment in an α-position.
- Miller, A.O.,Furin, G. G.
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p. 247 - 272
(2007/10/02)
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- REACTIONS OF PENTAFLUOROPHENYLHYDRAZINE AND SOME OF ITS N'-ACYL DERIVATIVES WITH COMPOUNDS CONTAINING A TRICHLOROMETHYL GROUP IN THE PRESENCE OF ALUMUNIUM CHLORIDE
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The reactions of pentafluorophenylhydrazine and also of N'-benzoyl-, N'-pentafluorobenzoyl-, and N'-acetylpentafluorophenylhydrazines and decafluorohydrazobenzene with CCl3R (R=Cl, C6H5, C6F5) in the presence of aluminium chloride were investigated.The main products from the reaction of pentafluorophenylhydrazine with the reagents were N-pentafluorophenylhydrazonodichloromethane and N-pentafluorophenylhydrazonoaryl chlorides.Derivatives of 1,3,4-oxadiazol-2-in-5-one were formed in the reactions of N'-acylpentafluorophenylhydrazines with carbon tetrachloride in the pres ence of aluminium chloride.When heated with carbon tetrachloride and aluminium chloride, decafluorohydrazobenzene disproportionates with the formation of decafluoroazobenzene and pentafluoroaniline.
- Petrova, T. D.,Ryabichev, A. G.,Savchenko, T. I.,Platonov, V. E.,Mamatyuk, V. I.,et al.
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p. 1168 - 1176
(2007/10/02)
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- ortho-Disubstituted F-Benzenes. III. Preparation of (F-Benzo)heterocyclic Compounds from F-Benzoic Acid and F-Phenol, and the Reactions of Some Intermediary F-Benzoyl- and F-Phenoxy Compounds
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With the intention of achieving the selective ortho-substitution of F-benzoic acid and F-phenol via intramolecular nucleophilic cyclization, preparation of some requisite precursory F-benzoyl- and F-phenoxy compounds and their nucleophilic cyclization reactions were examined. 1,2-(F-Benz)isoxazol-3(2H)-one, 2-(p-tolyl)-1,2-(F-benz)isoxazol-3(2H)-one, 1,3-dimethyl(F-benzo)pyrimidine-2,4(1H,3H)-dione, and 1,4-(F-benz)oxazin-3(2H)-one were obtained from the respective precursory F-benzohydroxamic acid, N-(p-tolyl)-N-hydroxy-F-benzamide, N,N'-dimethyl-N-(F-benzoyl)urea, and 2-(F-phenoxy)acetohydrazide.Attempted cyclizations of 2-(F-phenoxy)acetohydroxamic acid and (F-phenoxy)acetic acid were accompanied by simultaneous ring-opening and resulted in the formation of the identical product : (2-hydroxy-F-phenoxy)acetic acid.Transamidation of ethyl F-benzoate with hydroxylamine failed to give F-benzohydroxamic acid, which was then obtained by the catalytic debenzylation of N-benzyloxy-F-benzamide.
- Inukai, Yoshinari,Oono, Yoshitsugu,Sonoda, Takaaki,Kobayashi, Hiroshi
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p. 3447 - 3452
(2007/10/02)
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