176969-34-9Relevant articles and documents
PRODUCING METHOD FOR 3-DIFLUOROMETHYLPYRAZOLE COMPOUND, PRODUCING METHOD FOR 3-DIFLUOROMETHYLPYRAZOLE-4-CARBOXYLIC ACID COMPOUND, AND PYRAZOLIDINE COMPOUND
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Paragraph 0185-0189, (2021/03/05)
Provided are producing methods for a 3-difluoromethylpyrazole compound and a 3-difluoromethylpyrazole-4-carboxylic acid compound, which include, in a reaction solvent containing a specific solvent, subjecting a difluoroacetyl group-containing compound, a hydrazine compound, and formaldehyde to a cyclocondensation reaction, and subsequently oxidizing the obtained pyrazole compound precursor, and a pyrazolidine compound represented by a specific formula in these producing methods.
Preparation method and application of pyrazole derivative
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Paragraph 0037-0038, (2020/05/08)
The invention relates to a preparation method of a pyrazole derivative. The compound shown in the formula I reacts with a silanization reagent shown in a formula II to generate an intermediate productshown in a formula III, the intermediate product shown in the formula III reacts with a halogenated acid derivative shown in a formula IV to generate a halogenated compound shown in a formula V, andthe halogenated compound shown in the formula V reacts under acidic conditions to generate a pyrazole derivative shown in a formula VI. The preparation method of the pyrazole derivative is suitable for industrial production.
3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxylate compounds, and preparation method and application thereof
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Paragraph 0028; 0031-0032, (2020/01/25)
The invention discloses 3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxylate compounds, and a preparation method and an application thereof. The 3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxylatecompounds are 2-(benzoyloxy)ethyl 3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxylate compounds, and have a structural formula represented by formula (I) shown in the description; and in the formula(I), a substituent group R is a phenyl group or a substituted phenyl group, and a substituent group on the benzene ring of the substituted phenyl group is halogen or a C1-C3 alkyl group. The 2-(benzoyloxy)ethyl 3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxylate compounds are new compounds with bactericidal activity, have a good inhibition rate on Fusarium graminerum at the concentration of 50ppm, and provide a basis for research and development of new pesticides.