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  • 3655-05-8 Structure
  • Basic information

    1. Product Name: BOC-GLY-ONP
    2. Synonyms: BOC-GLY-ONP;BOC-GLYCINE 4-NITROPHENYL ESTER;BOC-GLYCINE P-NITROPHENYL ESTER;BOC-GLYCINE-ONP;4-nitrophenyl N-[(1,1-dimethylethoxy)carbonyl]glycinate;N-T-BOC-GLYCINE P-NITROPHENYL ESTERCRYST ALLINE;N-alpha-t-Butyloxycarbonyl-glycine p-nitrophenyl ester;N-(tert-Butoxycarbonyl)glycine 4-nitrophenyl ester
    3. CAS NO:3655-05-8
    4. Molecular Formula: C13H16N2O6
    5. Molecular Weight: 296.28
    6. EINECS: 222-900-4
    7. Product Categories: Amino Acid Derivatives
    8. Mol File: 3655-05-8.mol
  • Chemical Properties

    1. Melting Point: 71 °C
    2. Boiling Point: 457°Cat760mmHg
    3. Flash Point: 230.2°C
    4. Appearance: /
    5. Density: 1.267g/cm3
    6. Vapor Pressure: 1.54E-08mmHg at 25°C
    7. Refractive Index: 1.533
    8. Storage Temp.: 2-8°C
    9. Solubility: N/A
    10. PKA: 10.65±0.46(Predicted)
    11. CAS DataBase Reference: BOC-GLY-ONP(CAS DataBase Reference)
    12. NIST Chemistry Reference: BOC-GLY-ONP(3655-05-8)
    13. EPA Substance Registry System: BOC-GLY-ONP(3655-05-8)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany: 3
    5. RTECS:
    6. F: 8
    7. HazardClass: N/A
    8. PackingGroup: N/A
    9. Hazardous Substances Data: 3655-05-8(Hazardous Substances Data)

3655-05-8 Usage

Chemical Properties

Brown powder

Uses

Substrate for chymotrypsin and trypsin.

Check Digit Verification of cas no

The CAS Registry Mumber 3655-05-8 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 3,6,5 and 5 respectively; the second part has 2 digits, 0 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 3655-05:
(6*3)+(5*6)+(4*5)+(3*5)+(2*0)+(1*5)=88
88 % 10 = 8
So 3655-05-8 is a valid CAS Registry Number.
InChI:InChI=1/C13H16N2O6/c1-13(2,3)21-12(17)14-8-11(16)20-10-6-4-9(5-7-10)15(18)19/h4-7H,8H2,1-3H3,(H,14,17)

3655-05-8 Well-known Company Product Price

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  • Detail
  • Aldrich

  • (15117)  Boc-Gly-ONp  ≥98.0% (HPLC)

  • 3655-05-8

  • 15117-5G

  • 732.42CNY

  • Detail

3655-05-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 15, 2017

Revision Date: Aug 15, 2017

1.Identification

1.1 GHS Product identifier

Product name (4-nitrophenyl) 2-[(2-methylpropan-2-yl)oxycarbonylamino]acetate

1.2 Other means of identification

Product number -
Other names Boc-glycine 4-nitrophenyl ester

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:3655-05-8 SDS

3655-05-8Relevant articles and documents

Kilogram-Scale Synthesis of Osteogenic Growth Peptide (10-14) Using a Fragment Coupling Approach

Zhang, Teng,Chen, Zhenxing,Tian, Yan,Han, Bin,Zhang, Ning,Song, Wei,Liu, Zhulan,Zhao, Jinli,Liu, Jianli

, p. 1257 - 1262 (2015/09/28)

Kilogram-scale synthesis of a bioactive pentapeptide in solution by "3 + 2" fragment coupling strategy has been successively accomplished in the development of OGP (10-14), a minimal OGP-derived sequence that retains the full proliferative activity of the osteogenic growth peptide. The synthetic scheme, coupling conditions, and scaling-up of the process are systematically studied; the epimerization of the tripeptide fragment and pentapeptide are also evaluated.

Synthesis of a novel cyclic prodrug of S -allyl-glutathione able to attenuate LPS-induced ROS production through the inhibition of MAPK pathways in U937 cells

Patruno, Antonia,Fornasari, Erika,Di Stefano, Antonio,Cerasa, Laura S.,Marinelli, Lisa,Baldassarre, Leonardo,Sozio, Piera,Turkez, Hasan,Franceschelli, Sara,Ferrone, Alessio,Di Giacomo, Viviana,Speranza, Lorenza,Felaco, Mario,Cacciatore, Ivana

, p. 66 - 74 (2015/02/02)

A novel cyclic prodrug of S-allyl-glutathione (CP11), obtained by using an acyloxy-alkoxy linker, was estimated for its pharmacokinetic and biological properties. The stability of CP11 was evaluated at pH 1.2, 7.4, in simulated fluids with different concentrations of enzymes, and in human plasma. The anti-inflammatory ability of CP11 was assessed in U937 cells, an immortalized human monocyte cell line. Results showed that CP11 is stable at acidic pH showing a possible advantage for oral delivery due to the longer permanence in the stomach. Having a permeability coefficient of 2.49 × 10-6 cm s-1, it was classified as discrete BBB-permeable compound. Biological studies revealed that CP11 is able to modulate inflammation mediated by LPS in U937 cells preventing the increase of ROS intracellular levels through interaction with the MAPK pathway.

Pesticidal compositions and processes related thereto

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Page/Page column 91, (2016/01/09)

This document discloses molecules having the following formula (“Formula One”): and processes associated therewith.

PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO

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Page/Page column, (2014/06/25)

This document discloses molecules having the following formula (“Formula One”): and processes associated therewith.

PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO

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Page/Page column 90, (2014/07/08)

This document discloses molecules having the following formula ("Formula One"): and processes associated therewith.

PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO

-

Paragraph 0430-0431, (2014/06/25)

This document discloses molecules having the following formula (“Formula One”): and processes associated therewith.

PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO

-

Page/Page column 91, (2014/07/08)

This document discloses molecules having the following formula ("Formula One") and processes associated therewith.

PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO

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Paragraph 0596; 0597, (2014/06/25)

This document discloses molecules having the following formula (“Formula One”): and processes associated therewith.

PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO

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Page/Page column 48, (2013/02/28)

This document discloses molecules having the following formula (“Formula One”): and processes associated therewith.

Oxaziridine-mediated oxyamination of indoles: An approach to 3-aminoindoles and enantiomerically enriched 3-aminopyrroloindolines

Benkovics, Tamas,Guzei, Ilia A.,Yoon, Tehshik P.

supporting information; experimental part, p. 9153 - 9157 (2011/02/19)

A radical solution: A highly regioselective copper(II)-catalyzed oxyamination of N-acyl indoles with oxaziridines gave aminal products that could be converted in a single step into 3-aminoindoles and 3-aminopyrroloindolines (see scheme). When a chiral N-acyl group was used, the core fragment of some architecturally fascinating pyrroloindoline alkaloids was formed with 91% ee. Bs=benzenesulfonyl, Moc=methoxycarbonyl. Copyright

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