403-41-8

Basic information

• Product Name: 1-(4-Fluorophenyl)ethanol
• Synonyms: 4-fluoro-α-methylbenzyl alcohol;4-Fluoro-alpha-methylbenzyl alcohol 97%;4-Fluoro-alpha-methylbenzylalcohol97%;1-(p-Fluorophenyl)ethyl alcohol;4-Fluoro-α-methylbenzenemethanol;α-Methyl-4-fluorobenzenemethanol;α-Methyl-4-fluorobenzyl alcohol;4-Fluoro-alpha-methylbenzyl alcohol,99%
• CAS NO: 403-41-8
• Molecular Formula: C₈H₉FO
• Molecular Weight: 140.15
• EINECS: 206-959-3
• Product Categories: Benzhydrols, Benzyl & Special Alcohols;Fluorine Compounds;Phenols;Alcohols;C7 to C8;Oxygen Compounds;Fluorine series
• Mol File: 403-41-8.mol
• Article Data: 507

Chemical Properties

• Melting Point: 9 °C
• Boiling Point: 90-92 °C7 mm Hg(lit.)
• Flash Point: 195 °F
• Appearance: clear light yellow liquid
• Density: 1.109 g/mL at 25 °C(lit.)
• Vapor Pressure: 0.0829mmHg at 25°C
• Refractive Index: n20/D 1.501(lit.)
• Storage Temp.: 2-8°C
• PKA: 14.36±0.20(Predicted)
• CAS DataBase Reference: 1-(4-Fluorophenyl)ethanol(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4-Fluorophenyl)ethanol(403-41-8)
• EPA Substance Registry System: 1-(4-Fluorophenyl)ethanol(403-41-8)

Safety Data

• Hazard Codes: Xi,F,Xn
• Statements: 36/37/38-20/21/22
• Safety Statements: 26-36-36/37/39
• WGK Germany: 3
• HazardClass: IRRITANT
• Hazardous Substances Data: 403-41-8(Hazardous Substances Data)

Usage

Chemical Properties

clear light yellow liquid

General Description

4-Fluoro-α-methylbenzyl alcohol was isolated as phytocomponent in the methanolic extracts of the whole plant of Thevetia peruviana.

InChI:InChI=1/C8H9FO/c1-6(10)7-2-4-8(9)5-3-7/h2-6,10H,1H3

Upstream product

• 917-64-6 methyl magnesium iodide 
• 459-57-4 4-fluorobenzaldehyde 
• 75-16-1 methylmagnesium bromide 
• 75-89-8 2,2,2-trifluoroethanol 
• 456-16-6 1-(1-chloroethyl)-4-fluorobenzene 
• 109-78-4 3-Hydroxypropionitrile 
• 18511-62-1 4-fluorostyrene oxide 
• 75908-73-5 (+/-)-2-(4-flurophenyl)propanoic acid 
• 403-42-9 1-(4-fluorophenyl)ethanone 
• 405-99-2 para-fluorostyrene 
• 67-63-0 isopropyl alcohol 
• 108-22-5 Isopropenyl acetate 
• 1260183-56-9 C₁₁H₁₇FOSi 
• 766-98-3 1-ethynyl-4-fluorobenzene 

Downstream Products

• 456-16-6 1-(1-chloroethyl)-4-fluorobenzene 
• 2063-74-3 4,4'-(1,1'-oxybis(ethane-1,1-diyl))bis(fluorobenzene) 
• 65130-46-3 1-(4-fluorophenyl)ethyl bromide 
• 111662-72-7 1-(4-fluorophenyl)ethyl methyl ether 
• 111662-74-9 1-(4-fluorophenyl)ethyl ethyl ether 
• 172585-57-8 (R)-acetic acid 1-(4-fluoro-phenyl)-ethyl ester 
• 403-41-8 (S)-1-(4-fluorophenyl)ethan-1-ol 
• 403-42-9 1-(4-fluorophenyl)ethanone 
• 403-41-8 (R)-1-(4-fluorophenyl)ethan-1-ol 
• 2928-12-3 rac-1-(4-fluorophenyl)ethyl acetate 
• 960391-72-4 1,3-diphenyl-2-[1-(4-fluorophenyl)ethyl]propane-1,3-dione 
• 219119-79-6 (S)-1-(4-fluorophenyl)ethyl propionate 
• 511227-97-7 (R)-1-(4-fluorophenyl)ethyl propionate 

Relevant articles and documents

N-Propylphthalimide-Substituted Silver(I) N-Heterocyclic Carbene Complexes and Ruthenium(II) N-Heterocyclic Carbene Complexes: Synthesis and Transfer Hydrogenation of Ketones

This study deals with the synthesis of N-propylphthalimide substituted Ag(I)-N-heterocyclic carbene (NHC) complexes and N-propylphthalimide substituted Ru(II)-NHC complexes in the transfer hydrogenation of ketones. The Ag(I)-NHC complexes were synthesized

Ru(ii)-N-heterocyclic carbene complexes: Synthesis, characterization, transfer hydrogenation reactions and biological determination

A series of ruthenium(ii) complexes with N-heterocyclic carbene ligands were successfully synthesized by transmetalation reactions between silver(i) N-heterocyclic carbene complexes and [RuCl2(p-cymene)]2 in dichloromethane under Ar

Cinchona-Alkaloid-Derived NNP Ligand for Iridium-Catalyzed Asymmetric Hydrogenation of Ketones

Most ligands applied for asymmetric hydrogenation are synthesized via multistep reactions with expensive chemical reagents. Herein, a series of novel and easily accessed cinchona-alkaloid-based NNP ligands have been developed in two steps. By combining [Ir(COD)Cl]2, 39 ketones including aromatic, heteroaryl, and alkyl ketones have been hydrogenated, all affording valuable chiral alcohols with 96.0-99.9% ee. A plausible reaction mechanism was discussed by NMR, HRMS, and DFT, and an activating model involving trihydride was verified.

Application of nitrogen-containing heterocyclic mercaptan cuprous compound in photocatalytic reaction of carbonyl compound

The invention discloses an application of a nitrogen-containing heterocyclic mercaptan cuprous compound in a photocatalytic reaction of a carbonyl compound, relates to the technical field of application of photocatalysts; in particular, photocatalytic reduction reaction is carried out on the carbonyl compound by adopting the nitrogen-containing heterocyclic mercaptan cuprous compound as a photocatalyst to prepare an alcohol compound. The nitrogen-containing heterocyclic mercaptan cuprous compound is used as the photocatalyst for the photocatalytic reduction reaction of the carbonyl compound, visible light is successfully catalyzed to induce reduction of the carbonyl compound into the alcohol compound, the catalyst is low in price and good in catalytic effect, and the production cost can be reduced.