50390-51-7Relevant articles and documents
Synthesis of novel chiral heterometallic terpene oximates: Unusual generation of an aluminium enolate by a cooperative effect
Fernández-Millán, María,Temprado, Manuel,Cano, Jesús,Cuenca, Tomás,Mosquera, Marta E.G.
, p. 10514 - 10518 (2016)
Al-K heterometallic terpene oximate derivatives with uncommon structural features are reported. These species react with an aryl ketone leading to heterometallic enolates via an unusual route. Isolation of a remarkable heterometallic Al-K enolate confirms the cooperative mechanism proposed by DFT calculations, where the oximate ligand has a prominent role. From these enolates the formation of new C-C bonds is straightforward.
Palladium-Catalyzed Synthesis of α-Methyl Ketones from Allylic Alcohols and Methanol
Biswal, Priyabrata,Chandrasekhar, Vadapalli,Meher, Sushanta Kumar,Samser, Shaikh,Venkatasubbaiah, Krishnan
supporting information, (2021/11/01)
One-pot synthesis of α-methyl ketones starting from 1,3-diaryl propenols or 1-aryl propenols and methanol as a C1 source is demonstrated. This one-pot isomerization-methylation is catalyzed by commercially available Pd(OAc)2 with H2O as the only by-product. Mechanistic studies and deuterium labelling experiments indicate the involvement of isomerization of allyl alcohol followed by methylation through a hydrogen-borrowing pathway in these isomerization-methylation reactions.
Rhenium(I)-Catalyzed C-Methylation of Ketones, Indoles, and Arylacetonitriles Using Methanol
Shee, Sujan,Kundu, Sabuj
, p. 6943 - 6951 (2021/05/29)
A ReCl(CO)5/MeC(CH2PPh2)3 (L2) system was developed for the C-methylation reactions utilizing methanol and base, following the borrowing hydrogen strategy. Diverse ketones, indoles, and arylacetonitriles underwent mono-and dimethylation selectively up to 99% yield. Remarkably, tandem multiple methylations were also achieved by employing this catalytic system.
