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57-87-4

57-87-4

Identification

  • Product Name:Ergosterol

  • CAS Number: 57-87-4

  • EINECS:200-352-7

  • Molecular Weight:396.657

  • Molecular Formula: C28H44O

  • HS Code:29334900

  • Mol File:57-87-4.mol

Synonyms:Ergosterol (8CI);(22E,24R)-Ergosta-5,7,22-trien-3b-ol;(24R)-Ergosta-5,7,22-trien-3b-ol;24-Methylcholesta-5,7,22-trien-3b-ol;24R-Methylcholesta-5,7,22E-trien-3b-ol;24a-Methyl-22E-dehydrocholesterol;3b-Hydroxyergosta-5,7,22-triene;Ergosterin;Provitamin D2;Reishi Mushroom PE;

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Safety information and MSDS view more

  • Pictogram(s):VeryT+

  • Hazard Codes:T+,T,Xn

  • Signal Word:No signal word.

  • Hazard Statement:none

  • First-aid measures: General adviceConsult a physician. Show this safety data sheet to the doctor in attendance.If inhaled If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician. In case of skin contact Wash off with soap and plenty of water. Consult a physician. In case of eye contact Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician. If swallowed Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician. /SRP:/ Immediate first aid: Ensure that adequate decontamination has been carried out. If patient is not breathing, start artificial respiration, preferably with a demand valve resuscitator, bag-valve-mask device, or pocket mask, as trained. Perform CPR if necessary. Immediately flush contaminated eyes with gently flowing water. Do not induce vomiting. If vomiting occurs, lean patient forward or place on the left side (head-down position, if possible) to maintain an open airway and prevent aspiration. Keep patient quiet and maintain normal body temperature. Obtain medical attention. /Poisons A and B/

  • Fire-fighting measures: Suitable extinguishing media Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide. Wear self-contained breathing apparatus for firefighting if necessary.

  • Accidental release measures: Use personal protective equipment. Avoid dust formation. Avoid breathing vapours, mist or gas. Ensure adequate ventilation. Evacuate personnel to safe areas. Avoid breathing dust. For personal protection see section 8. Prevent further leakage or spillage if safe to do so. Do not let product enter drains. Discharge into the environment must be avoided. Pick up and arrange disposal. Sweep up and shovel. Keep in suitable, closed containers for disposal.

  • Handling and storage: Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Avoid exposure - obtain special instructions before use.Provide appropriate exhaust ventilation at places where dust is formed. For precautions see section 2.2. Store in cool place. Keep container tightly closed in a dry and well-ventilated place.

  • Exposure controls/personal protection:Occupational Exposure limit valuesBiological limit values Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at the end of workday. Eye/face protection Safety glasses with side-shields conforming to EN166. Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU). Skin protection Wear impervious clothing. The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace. Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique(without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands. The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it. Respiratory protection Wear dust mask when handling large quantities. Thermal hazards

Supplier and reference price view more

  • Manufacture/Brand
  • Product Description
  • Packaging
  • Price
  • Delivery
  • Purchase
  • Manufacture/Brand:Usbiological
  • Product Description:Ergosterol
  • Packaging:10g
  • Price:$ 340
  • Delivery:In stock
  • Buy Now
  • Manufacture/Brand:TRC
  • Product Description:Ergosterol
  • Packaging:100mg
  • Price:$ 120
  • Delivery:In stock
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  • Manufacture/Brand:TCI Chemical
  • Product Description:Ergosterol >95.0%(GC)
  • Packaging:5g
  • Price:$ 50
  • Delivery:In stock
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  • Manufacture/Brand:TCI Chemical
  • Product Description:Ergosterol >95.0%(GC)
  • Packaging:25g
  • Price:$ 177
  • Delivery:In stock
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  • Manufacture/Brand:Sigma-Aldrich
  • Product Description:Ergosterol European Pharmacopoeia (EP) Reference Standard
  • Packaging:
  • Price:$ 190
  • Delivery:In stock
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  • Manufacture/Brand:Sigma-Aldrich
  • Product Description:Ergosterol European Pharmacopoeia (EP) Reference Standard
  • Packaging:e1100000
  • Price:$ 190
  • Delivery:In stock
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  • Manufacture/Brand:Sigma-Aldrich
  • Product Description:Ergosterol ≥75%
  • Packaging:25g
  • Price:$ 268
  • Delivery:In stock
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  • Manufacture/Brand:Sigma-Aldrich
  • Product Description:Ergosterol ≥75%
  • Packaging:10g
  • Price:$ 129
  • Delivery:In stock
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  • Manufacture/Brand:Sigma-Aldrich
  • Product Description:Ergosterol ≥95.0% (HPLC)
  • Packaging:10g-f
  • Price:$ 125
  • Delivery:In stock
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  • Manufacture/Brand:Sigma-Aldrich
  • Product Description:Ergosterol ≥75%
  • Packaging:5g
  • Price:$ 75
  • Delivery:In stock
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Relevant articles and documentsAll total 11 Articles be found

v. Christiani,Pailer

, (1938)

Methods for preparing cholesterol, and derivatives and analogs thereof

-

Paragraph 0394-0395; 0406-008, (2021/04/07)

The present invention relates to the field of pharmaceutical chemistry, and in particular to methods of preparing cholesterol,and derivatives and analogs thereof. The cholesterol derivatives include, but not limited to, 7-dehydrocholesterol, 25-hydroxycholesterol, 25- hydroxy7dehydrocholesterol and ergosterol. In the invention, phytosterol can be used as a raw material to prepare the compound shown in the formula I through microbial conversion, and then cholesterol and the derivatives and analogues thereof are prepared.

METHODS AND COMPOSITIONS FOR THE TREATMENT OF ESTROGEN-DEPENDENT HYPERPROLIFERATIVE UTERINE DISORDERS

-

, (2010/04/30)

The present invention relates to the treatment of estrogen-dependent hyperproliferative uterine disorders including endometriosis, uterine fibroids, endometrial hyperplasia, uterine cancer, and their related symptoms by intravaginally administering at least two active agents selected from an aromatase inhibitor,an antiinflammatory agent, and a uterine-selective estrogen receptor antagonist. This combination therapy reduces local estrogen production, blocks local estrogen action, and suppresses inflammation locally, resulting in starvation of the estrogen-dependent diseased tissues, relief of related symptoms, and retardation of disease progression. Intravaginal delivery maximizes local inhibition of estrogen production without significantly affecting systemic circulating estogen levels. This results in enhanced clinical ellicacy and reduced side effects.

PREPARATION OF ANTIRACHITIC COMPOUNDS. I. KINETIC MODEL OF THE PHOTOISOMERIZATION PROCESS OF PROVITAMIN D2

Orlov, A. I.,Mikhailova, N. P.,Kosarev, A. A.,Vyunov, K. A.

, p. 829 - 834 (2007/10/02)

-

Process route upstream and downstream products

Process route

3β-acetoxy-5α,8α-(4-phenyl-1,2,4-triazolidine-3,5-dione-1,2-diyl)ergosta-6,22-diene
28421-56-9

3β-acetoxy-5α,8α-(4-phenyl-1,2,4-triazolidine-3,5-dione-1,2-diyl)ergosta-6,22-diene

Ergosterol
57-87-4

Ergosterol

1-Isobutyl-4-phenyl-[1,2,4]triazolidin-3-one

1-Isobutyl-4-phenyl-[1,2,4]triazolidin-3-one

Conditions
Conditions Yield
With diisobutylaluminium hydride; In hexane; toluene; at 0 ℃; for 0.166667h;
70%
3β-hydroxy-3',5'-dioxo-4'-phenyl-5,8<1',2'>-1',2',4'-triazolidino-5α,8α-ergosta-6,22-diene
10123-90-7

3β-hydroxy-3',5'-dioxo-4'-phenyl-5,8<1',2'>-1',2',4'-triazolidino-5α,8α-ergosta-6,22-diene

Ergosterol
57-87-4

Ergosterol

1-Isobutyl-4-phenyl-[1,2,4]triazolidin-3-one

1-Isobutyl-4-phenyl-[1,2,4]triazolidin-3-one

Conditions
Conditions Yield
With diisobutylaluminium hydride; In hexane; toluene; at 0 ℃; for 0.166667h;
51%
(22E,24R)-ergosta-4,7,22-triene-3-one
17398-57-1

(22E,24R)-ergosta-4,7,22-triene-3-one

Ergosterol
57-87-4

Ergosterol

Conditions
Conditions Yield
With aluminum isopropoxide; isopropyl alcohol;
benzoyloxy-3β (anisalamino-4' urazolo-1',2')-5α,8α ergostadiene-6,22
87530-77-6

benzoyloxy-3β (anisalamino-4' urazolo-1',2')-5α,8α ergostadiene-6,22

Ergosterol
57-87-4

Ergosterol

Conditions
Conditions Yield
With potassium hydroxide; In ethanol; water; for 2h; Heating;
29 % Turnov.
With potassium hydroxide; In ethanol; for 2h; Heating;
29 % Turnov.
Multi-step reaction with 2 steps
1: 98 percent / NaNO2 (10percent) / tetrahydrofuran; acetic acid
2: 10 percent Turnov. / KOH (0.8N) / ethanol / 2 h / Heating
With potassium hydroxide; sodium nitrite; In tetrahydrofuran; ethanol; acetic acid;
Multi-step reaction with 2 steps
1: 98 percent / 2,4-dinitro phenylhydrazine, p-toluenesulfonic acid monohydrate / H2O; tetrahydrofuran / 3 h / Heating
2: 18 percent Turnov. / KOH (0.8N) / ethanol / 2 h / Heating
With potassium hydroxide; toluene-4-sulfonic acid; (2,4-dinitro-phenyl)-hydrazine; In tetrahydrofuran; ethanol; water;
Multi-step reaction with 3 steps
1: 98 percent / 2,4-dinitro phenylhydrazine, p-toluenesulfonic acid monohydrate / H2O; tetrahydrofuran / 3 h / Heating
2: 95 percent / PhSeOOH / tetrahydrofuran / 0.33 h / Heating
3: 10 percent Turnov. / KOH (0.8N) / ethanol / 2 h / Heating
With potassium hydroxide; benzeneseleninic acid; toluene-4-sulfonic acid; (2,4-dinitro-phenyl)-hydrazine; In tetrahydrofuran; ethanol; water;
benzoyloxy-3β (urazolo-1',2')-5α,8α ergostadiene-6,22
87530-75-4

benzoyloxy-3β (urazolo-1',2')-5α,8α ergostadiene-6,22

Ergosterol
57-87-4

Ergosterol

Conditions
Conditions Yield
With potassium hydroxide; In ethanol; water; for 2h; Heating;
10 % Turnov.
With potassium hydroxide; In ethanol; for 2h; Heating;
10 % Turnov.
benzoyloxy-3β (benzalamino-4' urazolo-1',2')-5α,8α ergostadiene-6,22
87530-76-5

benzoyloxy-3β (benzalamino-4' urazolo-1',2')-5α,8α ergostadiene-6,22

Ergosterol
57-87-4

Ergosterol

Conditions
Conditions Yield
With potassium hydroxide; In ethanol; water; for 2h; Heating;
53 % Turnov.
With potassium hydroxide; In ethanol; for 2h; Heating;
53 % Turnov.
benzoyloxy-3β (p-nitrophenyl-4' urazolo-1',2')-5α,8α ergostadiene-6,22
87530-79-8

benzoyloxy-3β (p-nitrophenyl-4' urazolo-1',2')-5α,8α ergostadiene-6,22

Ergosterol
57-87-4

Ergosterol

Conditions
Conditions Yield
With potassium hydroxide; In ethanol; water; for 2h; Heating;
98 % Turnov.
With potassium hydroxide; In ethanol; for 2h; Heating;
98 % Turnov.
benzoyloxy-3β (p-nitrobenzalamino-4' urazolo-1',2')-5α,8α ergostadiene-6,22
87530-78-7

benzoyloxy-3β (p-nitrobenzalamino-4' urazolo-1',2')-5α,8α ergostadiene-6,22

Ergosterol
57-87-4

Ergosterol

Conditions
Conditions Yield
With potassium hydroxide; In ethanol; water; for 2h; Heating;
67 % Turnov.
With potassium hydroxide; In ethanol; for 2h; Heating;
62 % Turnov.
(22E)-5α,8α-(4'-phenyl)urazoloergosta-6,22-dien-3β-yl benzoate
28487-73-2,76035-90-0

(22E)-5α,8α-(4'-phenyl)urazoloergosta-6,22-dien-3β-yl benzoate

Ergosterol
57-87-4

Ergosterol

Conditions
Conditions Yield
With potassium hydroxide; In ethanol; water; for 2h; Heating;
37 % Turnov.
With potassium hydroxide; In ethanol; for 2h; Heating;
37 % Turnov.
C<sub>42</sub>H<sub>61</sub>N<sub>3</sub>O<sub>6</sub>S*C<sub>6</sub>H<sub>15</sub>N

C42H61N3O6S*C6H15N

Ergosterol
57-87-4

Ergosterol

Conditions
Conditions Yield
With lithium aluminium tetrahydride; In tetrahydrofuran; for 16h; Heating;
76%

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