594-19-4Relevant articles and documents
Method for producing, via organometallic compounds, organic intermediate products
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Page/Page column 4, (2008/06/13)
The present invention provides a process for preparing aryllithium compounds by reacting haloaliphatics with lithium metal to form a lithium alkyl and reacting the lithium alkyl with aromatic halogen compounds of formula (III) in a halogen-metal exchange reaction to form the corresponding lithium aromatics of formula (IV).
METHOD FOR PRODUCING ALKYL LITHIUM COMPOUNDS AND ARYL LITHIUM COMPOUNDS BY MONITORING THE REACTION BY MEANS OF IR-SPECTROSCOPY
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Page/Page column 10-11, (2008/06/13)
The invention relates to a method for producing alkyl lithium compounds and aryl lithium compounds by reacting lithium metal with alkyl or aryl halogenides in a solvent, the concentration of the alkyl/aryl halogenide and the alkyl/aryl lithium compound being detected according to an in-line measurement in the reactor by means of IR spectroscopy, and an exact recognition of the end point of the dosing of the halogenide constituents being carried out by evaluation of the IR measurement. Said method enables an optimum reactive process and reaction yield. The identification of the respective concentration of the educt and the product is a reliable reactive process. The yield of the reaction is also optimised by determining the end point of the halogenide dosing, as is the purity of the product due to a lower concentration thereof during the reaction.
Fluorous phosphines and process for their preparation
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, (2008/06/13)
A fluorous phosphine wherein the phosphor is coupled to at least one aryl or alkyl moiety, to which moiety a fluorous tail is coupled, wherein a spacer group, containing a non-carbon atom, is positioned between the aryl or alkyl moiety and the fluorous tail, a process for the preparation of said phosphines, metalcomplexes, catalysts and catalyst compounds therefrom and their use in catalysis.
Catalytic alkylation process
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, (2008/06/13)
This application concerns a process for alkylating, in a hydrocarbon solvent reaction medium, metalloidal substrates such as alkylating a chlorosilane with an alkyllithium containing 3 to 8 carbon atoms by conducting these reactions in the presence of a catalyst selected from primary and secondary alcohols, and their respective metal alkoxides, cyclic ethers, hydrocarbyl ethers, hydrocarbyl silyl ethers, and tertiary amines.
ASYMMETRIC OXIDATION OF SULFIDES MEDIATED BY CHIRAL TITANIUM COMPLEXES: MECHANISTIC AND SYNTHETIC ASPECTS
Zhao, S. H.,Samuel, O.,Kagan, H. B.
, p. 5135 - 5144 (2007/10/02)
Asymmetric oxidation of sulfides by hydroperoxides mediated by chiral titanium complexes was further developed.The effect of water was discussed as well as steric and electronic factors of aryl groups in aryl-S-alkyl oxidation.When aryl is replaced by 1-alkyne, the sulfoxude is still obtained with hihg ee.The enantioselectivity of oxidation is enhanced by using cumene hydroperoxide instead of t-butyl hydroperoxide (up to 96percent).The asymmetric oxidation was also run under catalytic conditions (with respect to the titanium complex) and beneficial effects were observed in the presence of molecular sieves in the reaction medium.
