620-93-9Relevant articles and documents
Studies on the amination of aryl chlorides with a monoligated palladium catalyst: Kinetic evidence for a cooperative mechanism
Jimeno, Ciril,Christmann, Ute,Escudero-Adan, Eduardo C.,Vilar, Ramon,Pericas, Miquel A.
, p. 16510 - 16516 (2012)
Combined spectroscopic, crystallographic, and kinetic studies of the mechanism of aromatic amination with the efficient dinuclear Pd precatalyst [Pd2Cl(μ-Cl)PtBu2(Bph-Me)] (Bph-Me=2′-methyl-[1, 1'-biphenyl]-2-yl) have revealed overlapping, yet cooperative, mechanistic scenarios, the relative weights of which are strongly influenced by the products formed as the reaction proceeds. The stability and evolution of the precatalyst in solution has been studied and several metalation pathways that point to a single monoligated intermediate have been identified. Our work sheds light on the nature of the catalytic species involved in the process and on the structure of the corresponding catalytic network. Two cycles for catalytic amination: Combined spectroscopic, crystallographic, and kinetic studies on the amination of p-chlorotoluene with p-toluidine with a monoligated Pd catalyst have revealed overlapping, yet cooperative, mechanistic scenarios, the relative weights of which are strongly influenced by the products formed as the reaction proceeds (see scheme; L=2′-methyl-[1,1'-biphenyl]-2-yl).
Mechanochemical synthesis of aromatic sulfonamides
Iaroshenko, Viktor O.,Mkrtchyan, Satenik
, p. 11029 - 11032 (2021/11/03)
A three-component Pd-catalysed aminosulfonylation reaction of K2S2O5 and amine with aryl bromides or aromatic carboxylic acids was developed. This strategy was developed to utilise mechanical energy and accommodate primary as well as secondary aliphatic and aromatic amines to provide a new shortcut to a wide range of sulfonamides. Studies on the scope and limitations of the reaction indicated its tolerance of a vast range of functional groups and many structural patterns. The reactions were scaled up to gram quantities.
Selective primary aniline synthesis through supported Pd-catalyzed acceptorless dehydrogenative aromatization by utilizing hydrazine
Lin, Wei-Chen,Yamaguchi, Kazuya,Yatabe, Takafumi
supporting information, p. 6530 - 6533 (2021/07/07)
By utilizing hydrazine (N2H4) as the nitrogen source in the presence of a hydroxyapatite-supported Pd nanoparticle catalyst (Pd/HAP), various primary anilines can be selectively synthesized from cyclohexanonesviaacceptorless dehydrogenative aromatization. The strong nucleophilicity of N2H4and the stability of the hydrazone intermediates can effectively suppress the formation of the undesired secondary aniline byproducts.
Diaromatic ring amide compound and application thereof
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Paragraph 0101; 0102; 0104-0106, (2021/07/01)
The invention relates to a diarylcyclic amide compound and application thereof. According to the invention, a high-purity solid can be obtained mainly by using the traditional recrystallization and column separation, the solid can be converted into corresponding diarylamine at high yield, especially high-purity liquid diarylcyclic secondary amine can be easily and conveniently obtained, and a high-purity organic semiconductor can be produced by the high-purity secondary amine on a large scale, and can be used in OPV or OLED devices. The chemical formula of the compound is shown in the specification, wherein R1 and R2 are H, D, F, or alkyl, alkoxy, fluoroalkyl, silyl, cycloalkyl, cycloalkoxy,-CN, -NO2 or phenyl with the carbon atom number smaller than 12; the dotted line is an oxygen atom, a sulfur atom, a silicon atom, a nitrogen atom, a carbon atom or a chemical bond for connecting two benzene rings or is nothing at all; and z is a protecting group and is selected from carbobenzoxy, t-butyloxycarbonyl, fluorene methoxycarbonyl, allyloxycarbonyl, trimethylsilylethoxycarbonyl, methoxycarbonyl, ethoxycarbonyl, phthaloyl, p-toluenesulfonyl, trifluoroacetyl, benzoyl, trityl, 2, 4-dimethoxybenzyl, p-methoxybenzyl and benzyl.