7205-60-9

Basic information

• Product Name: Benzene, 1-(ethylthio)-4-nitro-
• CAS NO: 7205-60-9
• Molecular Formula: C8H9NO2S
• Molecular Weight: 183.231
• Mol File: 7205-60-9.mol
• Article Data: 24

Chemical Properties

• CAS DataBase Reference: Benzene, 1-(ethylthio)-4-nitro-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, 1-(ethylthio)-4-nitro-(7205-60-9)
• EPA Substance Registry System: Benzene, 1-(ethylthio)-4-nitro-(7205-60-9)

Safety Data

• Hazardous Substances Data: 7205-60-9(Hazardous Substances Data)

Upstream product

• 591-96-8 penta-2,3-diene 
• 130436-15-6 2-methyl-2-butyl 4-nitrobenzenesulfenate 
• 130436-14-5 C₉H₁₁NO₃S 
• 598-25-4 Dimethylallene 
• 74-96-4 ethyl bromide 
• 13113-79-6 sodium 4-nitrobenzenethiolate 
• 636-98-6 p-nitrobenzene iodide 
• 994-45-6 triethyl(ethylthio)stannane 
• 824-78-2 4-nitrophenol sodium salt 
• 100-25-4 para-dinitrobenzene 
• 75-08-1 ethanethiol 
• 586-78-7 para-nitrophenyl bromide 
• 1849-36-1 para-nitrobenzenethiol 
• 110-81-6 Diethyl disulfide 

Downstream Products

• 1223498-32-5 (RS)-S-ethyl-S-(4-{[4-{[(1R,2R)-2-hydroxy-1-methylpropyl]amino}-5-(trifluoromethyl)-pyrimidin-2-yl]amino}phenyl)sulfoximide 
• 1223498-39-2 (R,S)-S-[4-({5-bromo-4-[(1R,2R)-(2-hydroxy-1-methylpropyl)amino]pyrimidin-2-yl}amino)phenyl]-S-ethylsulfoximide 
• 851007-68-6 (R,S)-S-[4-({5-bromo-4-[(1R,2R)-(2-hydroxy-1-methylpropyl)amino]pyrimidin-2-yl}amino)phenyl]-N-(ethoxycarbonyl)-S-ethylsulfoximide 
• 851008-62-3 (R,S)-N-(ethoxycarbonyl)-S-ethyl-S-(4-nitrophenyl)sulfoximide 
• 1223498-67-6 (S)-S-cyclopropyl-S-(4-{[4-{[(1R, 2R)-2-hydroxy-1-methylpropyl]oxy}-5-(trifluoromethyl)pyrimidin-2-yl]amino}phenyl)sulphoximide 
• 1223498-69-8 (R)-S-cyclopropyl-S-(4-{[4-{[(1R, 2R)-2-hydroxy-1-methylpropyl]oxy}-5-(trifluoromethyl)pyrimidin-2-yl]amino}phenyl)sulphoximide 
• 7205-81-4 1-(ethylsulfonyl)-4-nitrobenzene 
• 1223498-83-6 C₁₈H₂₄F₃N₅O₂S 
• 1223498-82-5 C₁₈H₂₄F₃N₅O₂S 
• 1223498-81-4 C₁₇H₂₂F₃N₅O₂S 
• 1223498-78-9 C₁₇H₂₂F₃N₅O₂S 
• 1223498-63-2 (R,S)-S-(4-aminophenyl)-S-ethyl-N-(trifluoroacetyl)sulfoximide 
• 1223498-62-1 (R,S)-S-ethyl-S-(4-nitrophenyl)-N-(trifluoroacetyl)sulfoximide 
• 851008-74-7 (R,S)-S-ethyl-S-(4-nitrophenyl)sulfoximide 

Relevant articles and documents

C-S coupling with nitro group as leaving group via simple inorganic salt catalysis

An efficient and practical synthetic protocol to synthesize nonsymmetrical aryl thioethers by nucleophilic aromatic substitution (SNAr) reaction of nitroarenes by thiols with potassium phosphate as the catalyst is described. Various moderate to strong electron-withdrawing functional groups are tolerated by the system to provide thioethers in a good to excellent yields. We also showed that the present method allows access to 3 drug examples in a short reaction time. Finally, mechanistic studies suggest that the reaction may form the classic Meisenheimer complex through a two-step addition-elimination mechanism.

Copper nanoparticles supported on polyaniline-functionalized multiwall carbon nanotubes: An efficient and recyclable catalyst for synthesis of unsymmetric sulfides using potassium ethyl xanthogenate in water

A new and powerful polyaniline-functionalized carbon nanotube-supported copper(II) nanoparticle catalyst was successfully prepared and evaluated as a heterogeneous catalyst for the one-pot synthesis of unsymmetric thioethers by coupling of aryl, alkyl and benzyl halides using potassium ethyl xanthogenate as source of sulfur in water. All of these reactions gave the desired products in good to excellent yields. The catalyst is available, air-stable and can be reused several times without significant loss in its catalytic activity.

SULFOXIMINE-SUBSTITUTED ANILINOPYRIMIDINE DERIVATIVES AS CDK INHIBITORS, THE PRODUCTION THEREOF, AND USE AS MEDICINE

The invention relates to sulfoximine-substituted anilino-pyrimidine derivatives of formula (I). methods of production thereof, and use thereof as medication for the treatment of various diseases.