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Thiol ester

Thiol esters, also known as thioesters, are a class of organic compounds characterized by the functional group -C(=O)-S-, where a sulfur atom is bonded to a carbonyl group, replacing the oxygen atom found in regular esters. This structural modification imparts unique chemical properties to thioesters, including greater reactivity in acyl-transfer reactions, making them crucial intermediates in organic synthesis and biochemistry. Thioesters play a vital role in various biological processes, such as in the metabolism of fatty acids and the synthesis of polyketides and nonribosomal peptides, where they form high-energy intermediates that facilitate the transfer of acyl groups. In industrial applications, thioesters are used as additives in lubricants and polymers, benefiting from their stability and resistance to oxidative degradation.
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