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D(+)-Sucrose

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Name

D(+)-Sucrose

EINECS 200-334-9
CAS No. 57-50-1 Density 1.77 g/cm3
PSA 189.53000 LogP -5.39560
Solubility 1970 g/L (15 ºC) Melting Point 185-187 °C(lit.)
Formula C12H22O11 Boiling Point 697.1 °C at 760 mmHg
Molecular Weight 342.3 Flash Point 375.4 °C
Transport Information N/A Appearance White crystalline powder
Safety 24/25-37/39-26 Risk Codes 36/37/38
Molecular Structure Molecular Structure of 57-50-1 (Sucrose) Hazard Symbols IrritantXi
Synonyms

Sucrose(8CI);(+)-Sucrose;Amerfond;Beet sugar;Cane sugar;Carrare C 10;Confectioner's sugar;Frost Sugar;GNE 410;Granulated sugar;Khandsari;Manalox AS;Microse;NSC 406942;Rockcandy;Saccharose;Saccharum;Sucrose NF;Sugar;White sugar;a-D-Glucosyl-b-D-fructofuranoside;b-D-Fructofuranosyl a-D-glucopyranoside;

Article Data 114

D(+)-Sucrose Synthetic route

302905-28-8

2,3,3',4,6-penta-O-benzylsucrose

57-50-1

Sucrose

Conditions
ConditionsYield
With Amberlite IR-45(OH-); hydrogen; palladium on activated charcoal In methanol; ethyl acetate under 5688.78 Torr;100%
126-14-7

sucrose octaacetate

57-50-1

Sucrose

Conditions
ConditionsYield
magnesium oxide In methanol for 1h; Ambient temperature;90%
With sodium methylate In methanol at 20℃; for 3h; Inert atmosphere;90%
With methanol; potassium cyanide for 0.5h; Ambient temperature;75%
inulin

inulin

A

57-48-7

D-Fructose

B

57-50-1

Sucrose

Conditions
ConditionsYield
With niobic acid In water at 89.84℃; for 2h; Catalytic behavior; Reagent/catalyst; Autoclave; Inert atmosphere;A 87%
B n/a
53081-30-4

tetra-O-benzyl-α-D-galactosyl bromide

A

(2S,3S,4R)-3,4-di-O-benzyl-N-hexacosanoyl-1-O-(2,3,4,6-tetra-O-benzyl-α-D-galactopyranosyl)-2-amino-1,3,4-octadecanetriol

(2S,3S,4R)-3,4-di-O-benzyl-N-hexacosanoyl-1-O-(2,3,4,6-tetra-O-benzyl-α-D-galactopyranosyl)-2-amino-1,3,4-octadecanetriol

B

Sucrose

Sucrose

Conditions
ConditionsYield
With tetrahexylammonium bromide In N,N-dimethyl-formamide; toluene for 72h; Ambient temperature;A 74%
B 8.2%
inulin

inulin

A

69-65-8

mannitol

B

50-70-4

D-sorbitol

C

57-50-1

Sucrose

Conditions
ConditionsYield
With hydrogen In water at 89.84℃; under 15001.5 Torr; for 4h; Catalytic behavior; Reagent/catalyst; Pressure;A 41%
B 43%
C 6%
With hydrogen In water at 89.84℃; under 15001.5 Torr; for 4h;A 37%
B 36%
C 8.4%
inulin

inulin

A

470-23-5

D-fructose

B

69-65-8

mannitol

C

50-70-4

D-sorbitol

D

57-50-1

Sucrose

Conditions
ConditionsYield
With hydrogen In water at 89.84℃; under 15001.5 Torr; for 4h;A 8.5%
B 40%
C 39%
D 5.5%
13360-52-6

Cellobiose

A

50-99-7

D-glucose

B

57-50-1

Sucrose

Conditions
ConditionsYield
With sodium hydroxide In water at 130℃; for 6h; pH=8; pH-value; Inert atmosphere; Sealed tube;A 11.8%
B 10.1%
133-89-1

UDP-glucose

57-48-7

D-Fructose

57-50-1

Sucrose

Conditions
ConditionsYield
mit Hilfe von Enzym-Praeparaten aus Weizenkeimen oder gruenen Erbsen;
Biosynthese mit Hilfe von Sucrosesynthase aus Weizenkeimen;
With sucrose synthase In aq. phosphate buffer at 37℃; for 1h; pH=8.5; Enzymatic reaction;
141-46-8

Glycolaldehyde

57-50-1

Sucrose

Conditions
ConditionsYield
at 100℃; im Vakuum;
512-69-6

D-raffinose

57-50-1

Sucrose

Conditions
ConditionsYield
With sodium periodate; ethanol; water anschl. mit wss. Na2CO3;

D(+)-Sucrose Chemical Properties

Structure of D(+)-Sucrose (CAS NO.57-50-1):

Empirical Formula: C12H22O11
Molecular Weight: 342.2965
Nominal Mass: 342 Da
Average Mass: 342.2965 Da
Monoisotopic Mass: 342.116212 Da 
Index of Refraction: 1.656
Molar Refractivity: 70.85 cm3
Molar Volume: 192.8 cm3
Surface Tension: 113 dyne/cm
Density: 1.77 g/cm3
Flash Point: 375.4 °C
Enthalpy of Vaporization: 116.71 kJ/mol
Boiling Point: 697.1 °C at 760 mmHg
Vapour Pressure: 1.79E-22 mmHg at 25 °C
Melting point: 185-187 °C(lit.)
Storage tempreture: Store at RT.
Water solubility: 500 mg/mL
Appearance: White odorless crystalline or powdery solid    
IUPAC Name: (2R,3R,4S,5S,6R)-2-[(2S,3S,4S,5R)-3,4-Dihydroxy-2,5-bis(hydroxymethyl)oxolan-2-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol
Canonical SMILES: C(C1C(C(C(C(O1)OC2(C(C(C(O2)CO)O)O)CO)O)O)O)O
Isomeric SMILES: C([C@@H]1[C@H]([C@@H]([C@H]([C@H](O1)O[C@]2([C@H]([C@@H]([C@H](O2)CO)O)O)CO)O)O)O)O
InChI: InChI=1S/C12H22O11/c13-1-4-6(16)8(18)9(19)11(21-4)23-12(3-15)10(20)7(17)5(2-14)22-12/h4-11,13-20H,1-3H2/t4-,5-,6-,7-,8+,9-,10+,11-,12+/m1/s1
InChIKey: CZMRCDWAGMRECN-UGDNZRGBSA-N
Product Category of 4-Chloro-6,7-bis(2-methoxyethoxy)quinazoline (CAS NO.183322-18-1):
Oligosaccharide Compounds;Basic Sugars (Mono & Oligosaccharides);Biochemistry;Disaccharides;Sugars;Oligosaccharides

D(+)-Sucrose Uses

 D(+)-Sucrose (CAS NO.57-50-1) can be widely used in food, cosmetics, and medicine, and is also used for the analysis of standard testing. It has been used as the standard for organic elemental analysis, too.

D(+)-Sucrose Toxicity Data With Reference

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
domestic animals - goat/sheep LDLo oral 40gm/kg (40000mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION

GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"
Nutrition Abstracts and Reviews. Vol. 30, Pg. 503, 1960.
mouse LD50 intraperitoneal 14000mg/kg (14000mg/kg)   Pharmaceutical Chemistry Journal Vol. 15, Pg. 139, 1981.
rat LD50 oral 29700mg/kg (29700mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

LUNGS, THORAX, OR RESPIRATION: CYANOSIS

GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"
Toxicology and Applied Pharmacology. Vol. 7, Pg. 609, 1965.

D(+)-Sucrose Consensus Reports

Reported in EPA TSCA Inventory. EPA Genetic Toxicology Program.

D(+)-Sucrose Safety Profile

Mildly toxic by ingestion. An experimental teratogen. Mutation data reported. Vigorous reaction with nitric acid or sulfuric acid (forms carbon monoxide and carbon dioxide). When heated to decomposition it emits acrid smoke and irritating fumes.
Hazard Codes: IrritantXi
Risk Statements: 36/37/38 
R36/37/38: Irritating to eyes, respiratory system and skin.
Safety Statements: 24/25-37/39-26 
S24/25: Avoid contact with skin and eyes. 
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. 
S37/39: Wear suitable gloves and eye/face protection.

D(+)-Sucrose Standards and Recommendations

OSHA PEL: TWA Total Dust: 15 mg/m3; Respirable Fraction: 5 mg/m3
ACGIH TLV: TWA (nuisance particulate) 10 mg/m3 of total dust (when toxic impurities are not present, e.g., quartz <1%); Not Classifiable as a Human Carcinogen
NIOSH REL: (Sucrose, Respirable Fraction) TWA 5 mg/m3; (Sucrose, total dust): TWA 10 mg/m3

D(+)-Sucrose Specification

 D(+)-Sucrose , its cas register number is 57-50-1. It also can be called alpha-D-Glucopyranosyl beta-D-fructofuranoside ; beta-D-Fructofuranose-(2-1)-alpha-D-glucopyranoside ; Sucrose ; Saccharose ; and alpha-D-Glucopyranosyl beta-D-fructofuranoside . It is hazardous, so the first aid measures and others should be known. Such as: When on the skin: Should flush skin with plenty of water immediately for at least 15 minutes while removing contaminated clothing. Or in the eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. While, it's inhaled: Remove from exposure and move to fresh air immediately. Then you have the ingesting of the product: Wash mouth out with water. Notes to physician: Treat supportively and symptomatically.
In addition, D(+)-Sucrose (CAS NO.57-50-1) could be stable under normal temperatures and pressures. It is not compatible with strong oxidizing agents, and you must not take it with incompatible materials. And also prevent it to broken down into hazardous decomposition products: Carbon monoxide, carbon dioxide.

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