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Ethylenediamine dihydrochloride

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Ethylenediamine dihydrochloride

EINECS 206-369-6
CAS No. 333-18-6 Density 1.159g/cm3
PSA 52.04000 LogP 1.90840
Solubility 300 g/L (20 °C) in water Melting Point >300 °C(lit.)
Formula C2H8N2.2(HCl) Boiling Point 119.7 °C at 760 mmHg
Molecular Weight 133.021 Flash Point 33.9 °C
Transport Information N/A Appearance white crystalline powder
Safety 22-26-36/37-45 Risk Codes 22-36/37/38-42/43
Molecular Structure Molecular Structure of 333-18-6 (Ethylenediamine dihydrochloride) Hazard Symbols HarmfulXn
Synonyms

1,2-Ethanediamine,dihydrochloride (9CI);Ethylenediamine, dihydrochloride (8CI);1,2-Diaminoethane dihydrochloride;Chlor-ethamine;Dimethylenediaminedihydrochloride;Ethylenediamine hydrochloride;Ethylenediammonium dichloride;

Article Data 27

Ethylenediamine dihydrochloride Chemical Properties

IUPAC Name: Ethane-1,2-diamine dihydrochloride
Synonyms of Ethylenediamine hydrochloride (CAS NO.542-90-5) : 1,2-Diaminoethane dihydrochloride ; 1,2-Ethanediamine, dihydrochloride ; Chlor-ethamine ; Dimethylenediamine dihydrochloride ; Ethylenediamine dihydrochloride ; 1,2-Ethanediamine, hydrochloride (1:2)
Product Categories: Pharmaceutical Intermediates;Sulphur Derivatives
CAS NO:542-90-5
Molecular Formula:C2H10Cl2N2
Molecular Weight :133.020200 g/mol
Molecular Structure :
EINECS: 206-369-6 
Flash Point: 33.9 °C
Enthalpy of Vaporization: 37.98 kJ/mol
Boiling Point: 119.7 °C at 760 mmHg
Vapour Pressure: 15.8 mmHg at 25°C
Melting Point: >300 °C(lit.)
Water Solubility : 300 g/L (20 ºC)
Sensitive: Hygroscopic
Stability: Stable. Incompatible with strong oxidizing agents.
Appearance: Ethylenediamine hydrochloride (CAS NO.542-90-5) is white crystalline powder.

Ethylenediamine dihydrochloride Uses

 Ethylenediamine hydrochloride (CAS NO.542-90-5) is used as analytical reagents and curing agent, which is also used in dye synthesis.

Ethylenediamine dihydrochloride Production

Raw materials: Hydrochloric acid-->Ethylenediamine

Ethylenediamine dihydrochloride Toxicity Data With Reference

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 1064mg/kg (1064mg/kg)   Yakugaku Zasshi. Journal of Pharmacy. Vol. 97, Pg. 1117, 1977.
mouse LD50 oral 1620mg/kg (1620mg/kg)   Fundamental and Applied Toxicology. Vol. 3, Pg. 512, 1983.
mouse LD50 subcutaneous 940mg/kg (940mg/kg)   Arzneimittel-Forschung. Drug Research. Vol. 4, Pg. 649, 1954.
rabbit LD50 skin > 6400mg/kg (6400mg/kg)   Kiso to Rinsho. Clinical Report. Vol. 3, Pg. 512, 1983.
rat LD50 intramuscular 150mg/kg (150mg/kg)   Experimental Medicine and Surgery. Vol. 4, Pg. 223, 1946.
rat LDLo oral 500mg/kg (500mg/kg)   Journal of Pharmacology and Experimental Therapeutics. Vol. 90, Pg. 260, 1947.

Ethylenediamine dihydrochloride Consensus Reports

Reported in EPA TSCA Inventory.

Ethylenediamine dihydrochloride Safety Profile

Poison by intramuscular route. Moderately toxic by ingestion. Experimental teratogenic and reproductive effects. When heated to decomposition it emits very toxic fumes of HCl and NOx.

Hazard Codes HarmfulXn
Risk Statements 22-36/37/38-42/43
R22:Harmful if swallowed. 
R42/43:May cause sensitization by inhalation and skin contact. 
R36/37/38:Irritating to eyes, respiratory system and skin.
Safety Statements 22-26-36/37-45
S22:Do not breathe dust. 
S26: When Ethylenediamine hydrochloride (CAS NO.542-90-5) is used,in case of contact with eyes, rinse immediately with plenty of water and seek medical advice. 
S36/37:Wear suitable protective clothing and gloves. 
S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
WGK Germany 2
RTECS KV3850000
HS Code 29212100 

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