Pictet-Spengler Reactions of Tryptamine and Tryptophan with Cycloalkanones and Ketonic Mannich Bases

DOI: 10.1007/BF00809161

Source and publish data:

Monatshefte fur Chemie p. 851 - 856 (1985)

Update date:2022-08-04

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Authors:

Afsah, E.M.

Hammouda, M.

Hamama, W.S.

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Article abstract of DOI:10.1007/BF00809161

A Pictet-Spengler reaction of tryptamine (1) with cyclopentanone under physiological conditions gave 3-(cyclopentylideneaminoethyl)indole (3), which was cyclized to the 1-spirocyclic 1,2,3,4-tetrahydro-2-carboline (4).Treatment of (+/-)-tryptophan with cy

Full text of DOI:10.1007/BF00809161

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