Bioorganic and Medicinal Chemistry Letters p. 2463 - 2466 (1996)
Update date:2022-07-29
Topics:
Jarvest, Richard L.
Parratt, Martin J.
Debouck, Christine M.
Gorniak, Joselina G.
Jennings, L. John
Serafinowska, Halina T.
Strickler, James E.
Benzoxazinones have been discovered which are mechanism based inhibitors of HSV-1 protease with micromolar IC50 values. Formation of a monoadduct consistent with the acyl-enzyme complex was detected by mass spectroscopy. A parallel array synthesis was developed to explore 2-heteroatom substituted SAR.
View MoreShandong Hongxiang Zinc Co., Ltd
Contact:086-0311-66187879
Address:DaWang developing zone
ShangHai BMG Chemical Co., Ltd
Contact:+86-13524845543
Address:Room 602, no 291 sikai road shanghai
Contact:86-513-84128750/13773795976
Address:No.48.Youyi West Road ,Rudong Development Zone,Jiangsu Province,China
Changsha Huajing Powdery Material Technological Co., Ltd.
Contact:86-731-88879686
Address:Building 2, West Garden, Main Campus of Central South University, Changsha, Hunan Province, China
Tangshan Wisdom Trading Co.,Ltd
Contact:86 315 2222979
Address:No.41 BeiXinXi Road, Yangguang building 1-1102 , Tangshan, Hebei, China
Doi:10.1016/S0968-0896(02)00424-8
(2003)Doi:10.1021/jo01327a044
(1979)Doi:10.1016/S0040-4039(01)95149-4
(1978)Doi:10.1007/BF00955980
(1982)Doi:10.1039/jr9600003800
(1960)Doi:10.1016/j.bmcl.2005.07.061
(2005)
