Purine acyclic nucleosides. 6-dimethylamino-9-[(2-phenylalanylamido-1-substituted-ethoxy)methyl]purine s as candidate antivirals

Article abstract of DOI:10.1002/jps.2600741211

Several acyclic puromycin analogues containing hydrocarbon substituents on the 1'-position of the aminoethoxymethyl moiety were synthesized and tested for antiviral activity. The N-carbobenzoxy intermediate 7c was active in vitro against Mengo and Semliki Forest viruses.