A FACILE, STEREOCONTROLLED ENTRY TO KEY INTERMEDIATES FOR THIENAMYCIN SYNTHESIS FROM ETHYL (S)-3-HYDROXYBUTANOATE

DOI: 10.1246/cl.1985.1343

Source and publish data:

Chemistry Letters p. 1343 - 1346 (1985)

Update date:2022-07-30

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Authors:

Chiba, Toshiyuki

Nagatsuma, Masako

Nakai, Takeshi

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Article abstract of DOI:10.1246/cl.1985.1343

A new synthetic approach to optically active key intermediates for thienamycin synthesis is described which involves the highly stereocontrolled transformation of the 2-azetidinone obtained via the condensation of ethyl (S)-3-hydroxybutanoate with the N-s

Full text of DOI:10.1246/cl.1985.1343

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