6-(3,4-dichlorophenyl)-1-[(methyloxy)methyl]-3-azabicyclo[4.1.0]heptane: A new potent and selective triple reuptake inhibitor

DOI: 10.1021/jm100481d

Source and publish data:

Journal of Medicinal Chemistry p. 4989 - 5001 (2010)

Update date:2022-07-30

Topics:

Authors:

Micheli, Fabrizio

Cavanni, Paolo

Andreotti, Daniele

Arban, Roberto

Benedetti, Roberto

Bertani, Barbara

Bettati, Michela

Bettelini, Letizia

Bonanomi, Giorgio

Braggio, Simone

Carletti, Renzo

Checchia, Anna

Corsi, Mauro

Fazzolari, Elettra

Fontana, Stefano

Marchioro, Carla

Merlo-Pich, Emilio

Negri, Michele

Oliosi, Beatrice

Ratti, Emiliangelo

Read, Kevin D.

Roscic, Maja

Sartori, Ilaria

Spada, Simone

Tedesco, Giovanna

Tarsi, Luca

Terreni, Silvia

Visentini, Filippo

Zocchi, Alessandro

Zonzini, Laura

Di Fabio, Romano

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Article abstract of DOI:10.1021/jm100481d

A pharmacophore model for triple reuptake inhibitors and the new class of 1-(aryl)-6-[alkoxyalkyl]-3-azabicyclo[3.1.0]hexanes were recently reported. Further investigation in this area led to the identification of a new series of potent and selective trip

Full text of DOI:10.1021/jm100481d

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