HOCHSELEKTIVE ADDITIONEN VON 2-LITHIO-1,3-DITHIAN AN DIE FREIE CARBONYL-FUNKTION OFFENKETTIGER PARTIELL BLOCKIERTER KOHLENHYDRAT-DERIVATE

Article abstract of DOI:10.1016/S0040-4039(00)89223-0

The addition of 2-lithio-1,3-dithiane (1) to the unprotected carbonyl function of partially blocked carbohydrate derivatives is in those cases highly diastereoselective where it is possible to arrange the oxygen functions at the C-atoms 2 and 4 in such a formation that both together with the carbonyl oxygen can chelate the cation of 1.