Stereo- and Enantio-controlled Synthesis of Chiral Intermediates for the Total Synthesis of Thienamycin and Related β-Lactam Antibiotics from 3-Hydroxybutyrates

DOI: 10.1039/c39850001433

Source and publish data:

Journal of the Chemical Society. Chemical communications p. 1433 - 1435 (1985)

Update date:2022-07-31

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Authors:

Georg, Gunda I.

Gill, Harpal S.

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Article abstract of DOI:10.1039/c39850001433

The synthesis of (1'R,3S,4S)- and (1'R,3S,4R)-3-(1'-t-butyldimethylsilyloxyethyl)-4-hydroxymethyl-2-azetidinone from ethyl (S)-3-hydroxybutyrate is reported.

Full text of DOI:10.1039/c39850001433

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