2,5-Unsubstituted Pyrrolidines from Formaldehyde and Amino Acids through in situ Azomethine-ylide 1,3-Dipolar Cycloaddition to Alkenes

DOI: 10.1039/c39850001566

Source and publish data:

Journal of the Chemical Society. Chemical communications p. 1566 - 1567 (1985)

Update date:2022-09-26

Topics: Characterization Stereochemistry Workup and Isolation 1,3-Dipolar Cycloaddition In Situ Generation

Authors:

Joucla, Marc

Mortier, Jacques

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Article abstract of DOI:10.1039/c39850001566

Formaldehyde and α-amino acids such as sarcosine and glycine react with alkenes to give N-Me and N-H pyrrolidines via in situ generated azomethine-ylides.

Full text of DOI:10.1039/c39850001566

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