Synthesis and Evaluation of 2-Substituted 1-Methyl-1-(4-tolylsulfonyl)hydrazines as Antineoplastic Agents

DOI: 10.1021/jm00157a033

Source and publish data:

Journal of Medicinal Chemistry p. 1299 - 1301 (1986)

Update date:2022-08-05

Topics:

Authors:

Hrubiec, Robert T.

Shyam, Krishnamurthy

Cosby, Lucille A.

Furubayashi, Ryosuke

Sartorelli, Allan C.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00157a033

Several N-2 substituted 1-methyl-1-(4-tolylsulfonyl)hydrazines were synthesized and evaluated for antineoplastic activity against the L1210 leukemia and B16 melanoma.The most active compound to emerge from this study, 2-(methylsulfonyl)-1-methyl-1-(4-toly

Full text of DOI:10.1021/jm00157a033

Products guided by the article

Product name:2-(diphenylphosphinyl)-1-methyl-1-(4-tolylsulfonyl)hydrazine

Cas No:102396-54-3

R&D Labs maybe for 102396-54-3

Chengdu NoVi Biotechnology Co., Ltd.(expird)

Contact:13551243286/028-81458053

Address:NO.168-1-224 JULONG ROAD WUHOU DISTRICT, CHENGDU CITY,SICHUAN PROVINCE
Hunan Shineway Enterprise Co., Ltd.

Contact:+86-731-86303875

Address:118, Huanghua International Airport Road, Huanghua Town, Changsha, Hunan 410137, China
SHANXI JINJIN CHEMICAL INDUSTRIAL CO.,LTD

website:http://www.jinjingroup.com

Contact:86-574-13989382828

Address:Economic And Technological Development Zone,Hejin?City,Shanxi Province?,China
Aqua Chem Industry Co., Ltd

Contact:+86-515-88356562

Address:No.2, West Daqing Road, Yancheng, Jiangsu, China
Forsman Scientific(Beijing)co.,Ltd.

Contact:+86-10-64646565

Address:Rm No.1301, Building-2, No. A-13 Beiyuan Road, Chaoyang District Beijing, China, PR,

Relevant to this article

Synthesis of flexible polydendate ligands bearing 5′-substituted-6-carboxylic-2,2′-bipyridine subunits

Doi:10.1055/s-2002-31968
(2002)
Photomodulated chiral induction in helical azobenzene oligomers

Doi:10.1021/ol8004722
(2008)
Formation of quaternary carbon centers by highly regioselective hydroformylation with catalytic amounts of a reversibly bound directing group

Doi:10.1002/chem.201101186
(2011)
Three-Component Cascade Synthesis of Fully Substituted Trifluoromethyl Pyrroles via a Cu(II)/Rh(III)-Promoted Aza-Michael Addition/Trifluoromethylation Cyclization/Oxidation Reaction

Doi:10.1021/acs.joc.9b03470
(2020)
Mn(OAc)₃*2H₂O promoted addition of arylboronic acids to quinoxalin-2-ones

Doi:10.1016/j.tetlet.2017.12.085
(2018)
Regio- And stereoselective synthesis of alkyl allylic ethers via gold(l)-catalyzed intermodular hydroalkoxylation of allenes with alcohols

Doi:10.1021/ol800646h
(2008)

Article Doi