Synthesis and Evaluation of 2-Substituted 1-Methyl-1-(4-tolylsulfonyl)hydrazines as Antineoplastic Agents

DOI: 10.1021/jm00157a033

Source and publish data:

Journal of Medicinal Chemistry p. 1299 - 1301 (1986)

Update date:2022-08-05

Topics:

Authors:

Hrubiec, Robert T.

Shyam, Krishnamurthy

Cosby, Lucille A.

Furubayashi, Ryosuke

Sartorelli, Allan C.

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Article abstract of DOI:10.1021/jm00157a033

Several N-2 substituted 1-methyl-1-(4-tolylsulfonyl)hydrazines were synthesized and evaluated for antineoplastic activity against the L1210 leukemia and B16 melanoma.The most active compound to emerge from this study, 2-(methylsulfonyl)-1-methyl-1-(4-toly

Full text of DOI:10.1021/jm00157a033

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