Journal of Medicinal Chemistry p. 1413 - 1417 (1986)
Update date:2022-09-26
Topics:
DeBernardis, John F.
Winn, Martin
Arendsen, David L.
Kerkman, Daniel J.
Kyncl, John J.
A series of modifications to positions 1,2, and 4 of the tetralin ring of 5,6-dihydroxy-1-(2-imidazolinyl)tetralin (1, A-54741) succeeded in improving the separation of the potent α1 and α2 adrenergic agonism observed for the parent
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