Journal of Medicinal Chemistry p. 3511 - 3522 (1994)
Update date:2022-07-31
Topics:
Higley
Wilde
Maduskuie
Johnson
Pennev
Billheimer
Robinson
Gillies
Wexler
A series of 4,5-diaryl-2-(substituted thio)-1H-imidazoles has been synthesized and demonstrated to be potent inhibitors of acyl-CoA:cholesterol acyltransferase (ACAT). The design, synthesis, and structure-activity relationships for this series are reporte
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