Synthesis of the C16-C23 effector domain of FK-506 via copper-catalysed metallate rearrangement of an α-alkoxyalkenylcuprate

DOI: 10.1055/s-1995-3871

Source and publish data:

Synthesis p. 195 - 198 (1995)

Update date:2022-08-02

Topics:

Authors:

Jarowicki

Kocienski

Norris Norris

O'Shea O'Shea

Stocks Stocks

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1055/s-1995-3871

A 1,2-metallate rearrangement of the putative higher order cuprate 17 derived from reaction of the metallated dihydrofuran 15 with the homocuprate 16 occurred with clean inversion of configuration to give the alkenylcuprate 18. Methylation of 18 followed

Full text of DOI:10.1055/s-1995-3871

Products guided by the article

Product name:(2R)-2-<(4R)-2,2-dimethyl-1,3-dioxolan-4-yl>-1-(4-nitrobenzoyloxy)pent-4-ene

Cas No:1026896-06-9

R&D Labs maybe for 1026896-06-9

MTT Pharma & Bio-technology Co.,Ltd(expird)

Contact:+86-21-58407925

Address:Room2019, Building C, Tomson Center, No.158, Zhang Yang Road, Shanghai, China
CGeneTech (Suzhou, China) Co., Ltd.

Contact:+86-512-62956962

Address:Room 101，Bld C11,218 Xinghu Rd.,Suzhou industrial Park
Suzhou Tianma Specialty Chemicals Co.,Ltd

Contact:+86-512-68090577

Address:#199, Huayuan Rd, Mudu, Suzhou, Jiangsu, CHINA
Shanghai Sunway Pharmaceutical Technology Co.,Ltd.

Contact:+86-21-5161 3915

Address:Shanghai YangPu
Jiangxi Dongbang Pharmaceutical Co., Ltd.

Contact:+86-795-4433603, 4433388

Address:Fengxin Industrial Park, Fengxin County, Jiangxi Province, P.R.C

Relevant to this article

Synthesis and characterization of a novel liver-targeted prodrug of cytosine-1-β-D-arabinofuranoside monophosphate for the treatment of hepatocellular carcinoma

Doi:10.1021/jm0607449
(2006)
Pyrrolidine-3-carboxylic acids as endothelin antagonists. 2. Sulfonamide-based ET(A)/ET(B) mixed antagonists

Doi:10.1021/jm970101g
(1997)
Efficient asymmetric synthesis of unnatural β-amino acids

Doi:10.1055/s-2001-16745
(2001)
Synthesis and structure-activity relationships of 3,5-disubstituted 4,5- dihydro-6H-imidazo[1,5-a][1,4]benzodiazepin-6-ones at diazepam-sensitive and diazepam-insensitive benzodiazepine receptors

Doi:10.1021/jm00056a008
(1993)
A novel celecoxib analog UTX-121 inhibits HT1080 cell invasion by modulating membrane-type 1 matrix metalloproteinase

Doi:10.1016/j.bbrc.2019.10.092
(2020)
Design, synthesis, biological evaluation and docking studies of pterostilbene analogs inside PPARα

Doi:10.1016/j.bmc.2008.01.051
(2008)

Article Doi