Synthesis of the C16-C23 effector domain of FK-506 via copper-catalysed metallate rearrangement of an α-alkoxyalkenylcuprate

DOI: 10.1055/s-1995-3871

Source and publish data:

Synthesis p. 195 - 198 (1995)

Update date:2022-08-02

Topics:

Authors:

Jarowicki

Kocienski

Norris Norris

O'Shea O'Shea

Stocks Stocks

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1055/s-1995-3871

A 1,2-metallate rearrangement of the putative higher order cuprate 17 derived from reaction of the metallated dihydrofuran 15 with the homocuprate 16 occurred with clean inversion of configuration to give the alkenylcuprate 18. Methylation of 18 followed

Full text of DOI:10.1055/s-1995-3871

Products guided by the article

Product name:(2R)-2-<(4R)-2,2-dimethyl-1,3-dioxolan-4-yl>-1-(4-nitrobenzoyloxy)pent-4-ene

Cas No:1026896-06-9

R&D Labs maybe for 1026896-06-9

jiangsu haian chemical co.,ltd.

Contact:86-513-15851283853

Address:No.99,Changjiang West Road,Haian County,Jiangsu Province,China
Hebei Kangtai Pharmaceutical Co.,Ltd

Contact:+86-0317-3512963

Address:Wugang Road,Mengcun of Cangzhou City,Hebei Province ,China
Tianjin SPHINX SCIENTIFIC LAB.

Contact:+86-022-66211289

Address:Tianda high-tech Park. No.80,the 4th Avenue
Nanjing Zelang Medical Technology Co. Ltd

Contact:86-25-83063290/13770714480

Address:Ganjiabian 108# 01 Unit,701-702 room,Yao Hua Street,Qixia District,Nanjing,Jiangsu,China
Joyochem Co., Ltd.

website:https://sdjingyuan.lookchem.com/

Contact:86-531-82687998

Address:Factory Building 11, Jinan Comprehensive free trade zone, Shandong, China

Relevant to this article

Synthesis and characterization of a novel liver-targeted prodrug of cytosine-1-β-D-arabinofuranoside monophosphate for the treatment of hepatocellular carcinoma

Doi:10.1021/jm0607449
(2006)
Pyrrolidine-3-carboxylic acids as endothelin antagonists. 2. Sulfonamide-based ET(A)/ET(B) mixed antagonists

Doi:10.1021/jm970101g
(1997)
Efficient asymmetric synthesis of unnatural β-amino acids

Doi:10.1055/s-2001-16745
(2001)
Synthesis and structure-activity relationships of 3,5-disubstituted 4,5- dihydro-6H-imidazo[1,5-a][1,4]benzodiazepin-6-ones at diazepam-sensitive and diazepam-insensitive benzodiazepine receptors

Doi:10.1021/jm00056a008
(1993)
A novel celecoxib analog UTX-121 inhibits HT1080 cell invasion by modulating membrane-type 1 matrix metalloproteinase

Doi:10.1016/j.bbrc.2019.10.092
(2020)
Design, synthesis, biological evaluation and docking studies of pterostilbene analogs inside PPARα

Doi:10.1016/j.bmc.2008.01.051
(2008)

Article Doi