Quinolizidines-V. A novel synthetic route to Ipecac alkaloids through chemical incorporation of ethyl cincholoiponate derived from the cinchona alkaloid cinchonine

Article abstract of DOI:10.1016/S0040-4020(01)83119-7

A new synthetic route to (-)-emetine (1) and related Ipecac alkaloids has been exploited in terms of the synthesis of the tricyclic ester (-)-30 from ethyl cincholoiponate [(+)-4], a degradation product of the Cinchona alkaloid cinchonine (7). The steps i