8-Amino-3-benzyl-1,2,4-triazolopyrazines. Synthesis and Anticonvulsant Activity

DOI: 10.1021/jm00018a029

Source and publish data:

Journal of Medicinal Chemistry p. 3676 - 3679 (1995)

Update date:2022-08-02

Topics:

Authors:

Kelley, James L.

Linn, James A.

Bankston, Donald D.

Burchall, Christopher J.

Soroko, Francis E.

Cooper, Barrett R.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00018a029

Eleven substituted 8-amino-3-benzyl-1,2,4-triazolo<4,3,-a>pyrazines were synthesized and tested for anticonvulsant activity against maximal electroshock-induced seizures (MES) in rats.The compounds were prepared in four stages from the phenylacetonitriles

Full text of DOI:10.1021/jm00018a029

Products guided by the article

Product name:1,3-Difluoro-2-(2,2,2-triethoxy-ethyl)-benzene

Cas No:1027528-07-9

R&D Labs maybe for 1027528-07-9

Suzhou Health Chemicals Co., Ltd.

website:http://www.healthchems.com

Contact:13776257979

Address:No. 338, Jingang Avenue,
Hebei DaPeng Pharm & Chem Co., Ltd.

Contact:86-317-7298678,0576-88861898 88861908

Address:West Songmen Village, East Songmen Town, Wuqiao, Cangzhou, Hebei ,China
Tianjin Jiuri New Materials Co., Ltd.

Contact:+86-22-58889220

Address:C-5/6, Vison Hill, No.1 Gonghua Road, Huayuan Hi-tech Park, Tianjin, China.
SHIJIAZHUANG HENRYTE CHEMICALS CO,.LTD(expird)

Contact:+86-311-85208698 311-80837698

Address:NO.166, yuhua west road, SHIJIAZHUANG, China
SHIJIAZHUANG AGERUO-BIOTECH CO.LTD

Contact:+86-130-2866-6699

Address:Huaian east Road 158

Relevant to this article

Efficient Synthesis of a New Amino Acid, (2S,3R,4R)-4-Chloro-3-hydroxyproline

Doi:10.1246/bcsj.59.493
(1986)
A CONTRIBUTION TO THE CHEMISTRY OF PYRAZOLE-TYPE DIANHYDROPHENYLOSAZONES

Doi:10.1016/0008-6215(85)85007-2
(1985)
Novel pyromellitic diimide-based macrocycle with a linear π-electronic system and bis(phenylethynyl)pyromellitic diimide: Syntheses, structures, photophysical properties, and redox characteristics

Doi:10.1021/jo800283r
(2008)
Desmethoxymajusculamide C, a cyanobacterial depsipeptide with potent cytotoxicity in both cyclic and ring-opened forms

Doi:10.1021/np9001674
(2009)
3,4-Di-tert-butylthiophene 1,1-Dioxide, a Convenient Precursor of o-Di-tert-butylbenzene and Its Derivatives

Doi:10.1021/ja00227a069
(1988)
The Total Synthesis of (+/-)-cis- and trans-Trikentrin A

Doi:10.1071/CH9900329
(1990)

Article Doi