8-Amino-3-benzyl-1,2,4-triazolopyrazines. Synthesis and Anticonvulsant Activity

DOI: 10.1021/jm00018a029

Source and publish data:

Journal of Medicinal Chemistry p. 3676 - 3679 (1995)

Update date:2022-08-02

Topics:

Authors:

Kelley, James L.

Linn, James A.

Bankston, Donald D.

Burchall, Christopher J.

Soroko, Francis E.

Cooper, Barrett R.

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Article abstract of DOI:10.1021/jm00018a029

Eleven substituted 8-amino-3-benzyl-1,2,4-triazolo<4,3,-a>pyrazines were synthesized and tested for anticonvulsant activity against maximal electroshock-induced seizures (MES) in rats.The compounds were prepared in four stages from the phenylacetonitriles

Full text of DOI:10.1021/jm00018a029

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