Synthesis and Biological Activity of Substance P C-Terminal Hexapeptide Analogues: Structure-Activity Studies

Article abstract of DOI:10.1021/jm00157a028

A series of analogues of the C-terminal hexapeptide of substance P, modified at the glutaminyl residue, was synthesized and their relative activities as spasmogens were determined in the guinea pig ileum and rat colon muscularis mucosae preparations in vi