Enantiomers of 3-(3,4-Dihydroxyphenyl)- and 3-(3-Hydroxyphenyl)-N-n-propylpiperidine: Central Pre- and Postsynaptic Dopaminergic Effects and Pharmacokinetics

DOI: 10.1021/jm00160a016

Source and publish data:

Journal of Medicinal Chemistry p. 1889 - 1895 (1986)

Update date:2022-07-29

Topics:

Authors:

Rollema, Hans

Mastebroek, Dora

Wikstroem, Hakan

Svensson, Kjell

Carlsson, Arvid

Sundell, Staffan

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Article abstract of DOI:10.1021/jm00160a016

This study emphasizes the importance of the metabolic conversion of the enantiomers of 3-(3-hydroxyphenyl)-N-n-propylpiperidine (3-PPP) into their catechol analogues, the enantiomers of 3-(3,4-dihydroxyphenyl)-N-n-propylpiperidine. These isomers are both

Full text of DOI:10.1021/jm00160a016

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