Synthesis and biological action of the aminotetrahydroisoquinocarbazoles and related compounds: A new class of compounds with antiarrhythmic activity

DOI: 10.1021/jm00083a004

Source and publish data:

Journal of Medicinal Chemistry p. 816 - 822 (1992)

Update date:2022-08-04

Topics:

Authors:

Shimoji Shimoji

Tomita Tomita

Hashimoto

Saito Saito

Morisawa

Mizuno Mizuno

Yorikane

Koike Koike

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Article abstract of DOI:10.1021/jm00083a004

A series of 12-aminotetrahydroisoquinocarbazoles and related compounds were synthesized using an intramolecular Diels-Alder reaction and screened for antiarrhythmic activity in chloroform-induced ventricular arrhythmias in mice. Several compounds showed m

Full text of DOI:10.1021/jm00083a004

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