A one pot procedure for the synthesis of α-hydroxyamides from the corresponding α-hydroxyacids

Article abstract of DOI:10.1080/00397919208020850

α-Hydroxyamides are synthesized from the corresponding α-hydroxyacids by generation of the bis-trimethylsilyl derivative and treating it with oxalyl chloride. Following addition of the appropriate amine, the TMS ether is hydrolized in the workup to provid

Full text of DOI:10.1080/00397919208020850

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Synthetic Communications: An
International Journal for Rapid
Communication of Synthetic
Organic Chemistry
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A One Pot Procedure for the
Synthesis of α-Hydroxyamides
from the Corresponding α-
Hydroxyacids
Sarah E. Kelly a & Thomas G. LaCour a
a Process Research and Development Central
Research Division , Pfizer Inc. , Groton,
Connecticut, 06340
Published online: 23 Sep 2006.
To cite this article: Sarah E. Kelly & Thomas G. LaCour (1992) A One Pot Procedure
for the Synthesis of α-Hydroxyamides from the Corresponding α-Hydroxyacids,
Synthetic Communications: An International Journal for Rapid Communication of
Synthetic Organic Chemistry, 22:6, 859-869, DOI: 10.1080/00397919208020850
To link to this article: http://dx.doi.org/10.1080/00397919208020850
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